{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:18:53Z","timestamp":1790255933037,"version":"4.1.0"},"reference-count":68,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000196","name":"Canada Foundation for Innovation","doi-asserted-by":"publisher","award":["CFI-JELF 38412"],"award-info":[{"award-number":["CFI-JELF 38412"]}],"id":[{"id":"10.13039\/501100000196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["ReCognitION project"],"award-info":[{"award-number":["ReCognitION project"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015402","name":"Canada Research Coordinating Committee","doi-asserted-by":"publisher","award":["NFRFG-2022-00033"],"award-info":[{"award-number":["NFRFG-2022-00033"]}],"id":[{"id":"10.13039\/100015402","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Myositis-Netz"},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["ERT-174211"],"award-info":[{"award-number":["ERT-174211"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["FDN-167281"],"award-info":[{"award-number":["FDN-167281"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["OR2-189333"],"award-info":[{"award-number":["OR2-189333"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["101080249"],"award-info":[{"award-number":["101080249"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010275","name":"Deutsche Gesellschaft f\u00fcr Muskelkranke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010275","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","award":["FRQS-311186"],"award-info":[{"award-number":["FRQS-311186"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["OPTIMISTIC \/ 305697"],"award-info":[{"award-number":["OPTIMISTIC \/ 305697"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["184.034.019"],"award-info":[{"award-number":["184.034.019"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs","doi-asserted-by":"publisher","award":["950-232279"],"award-info":[{"award-number":["950-232279"]}],"id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000023","name":"Government of Canada","doi-asserted-by":"publisher","award":["CFREF-2022-00007"],"award-info":[{"award-number":["CFREF-2022-00007"]}],"id":[{"id":"10.13039\/501100000023","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neuromuscular Diseases"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Myotonic Dystrophy Type 1 (DM1), the most common genetic neuromuscular disorder in adults, poses significant challenges for drug development due to its multisystem nature and high clinical variability in symptoms and disease progression. With a growing number of therapies entering clinical trials, this study addresses the urgent need for biomarkers that can serve as surrogate endpoints.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We profiled 437 serum samples from adult DM1 patients collected at two timepoints of the OPTIMISTIC trial using bottom-up mass spectrometry with data-independent acquisition. Associations between protein expression, the disease-causing CTG-repeat and 25 clinical outcome measures were studied using linear mixed-effect models. All key study findings were validated in an independent cohort of 69 DM1 patients and 10 healthy controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 259 identified proteins, 161 showed significant associations with the CTG-repeat length (FDR\u2009&lt;\u20095%). Hypogammaglobulinemia was confirmed and shown to be worse in severely affected patients. A strong proteomic signature was associated with clinical measures of functional capacity, with the 6-Minute Walk Test showing the strongest signal (70 associations, FDR\u2009&lt;\u20095%). These novel associations reveal a compelling link between chronic inflammation and reduced functional capacity. A machine learning algorithm identified a minimal set of 13 proteins robustly reflecting both the underlying genetic defect and functional capacity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>DM1 induces a broad disease fingerprint in the serum proteome, predominantly affecting proteins of the immune system. A carefully selected panel of proteins showed the greatest potential to meet the statistical criteria required for surrogate endpoints in clinical trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/22143602251410443","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:53:38Z","timestamp":1768589618000},"page":"992-1013","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Large-scale proteomics profiling of peripheral blood of DM1 patients identifies biomarkers for disease severity and functional capacity"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4702-1330","authenticated-orcid":false,"given":"Dani\u00ebl","family":"van As","sequence":"first","affiliation":[{"name":"Radboud University Medical Center"},{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tine","family":"Claeys","sequence":"additional","affiliation":[{"name":"VIB-UGent Center for Medical Biotechnology, VIB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee","family":"Salz","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphi Van","family":"Haver","sequence":"additional","affiliation":[{"name":"VIB-UGent Center for Medical Biotechnology, VIB"},{"name":"Ghent University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Dufour","sequence":"additional","affiliation":[{"name":"VIB-UGent Center for Medical Biotechnology, VIB"},{"name":"Ghent University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber van","family":"Deelen","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolein","family":"Gloerich","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Gabriels","sequence":"additional","affiliation":[{"name":"VIB-UGent Center for Medical Biotechnology, VIB"},{"name":"Ghent University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter Jan","family":"Volders","sequence":"additional","affiliation":[{"name":"Limburg Clinical Research Center (LCRC), UHasselt"},{"name":"Laboratory of Molecular Diagnostics, Jessa Hospital, Hasselt, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Dobelmann","sequence":"additional","affiliation":[{"name":"University Hospital D\u00fcsseldorf, Heinrich Heine University D\u00fcsseldorf"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gangfuss","sequence":"additional","affiliation":[{"name":"University Duisburg-Essen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Ruck","sequence":"additional","affiliation":[{"name":"Ruhr University Bochum, BG University Hospital Bergmannsheil"},{"name":"BG University Hospital Bergmannsheil, Heimer Institute for Muscle Research, Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevieve","family":"Gourdon","sequence":"additional","affiliation":[{"name":"Centre de Recherche en Myologie"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Duchesne","sequence":"additional","affiliation":[{"name":"Integrated University Health and Social Services Centre of Saguenay\u2013Lac-Saint-Jean"},{"name":"Interdisciplinary Research Center in Rehabilitation and Social Integration (Cirris), Integrated University Health and Social Services Centre of the Capitale-Nationale, Quebec City, QC, Canada"},{"name":"CHU de Qu\u00e9bec - Universit\u00e9 Laval Research Center, Quebec City, Quebec, Canada"},{"name":"School of Rehabilitation Sciences, Faculty of Medicine; CHU de Qu\u00e9bec \u2013 Research Center, Laval University, Quebec City, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Gagnon","sequence":"additional","affiliation":[{"name":"Integrated University Health and Social Services Centre of Saguenay\u2013Lac-Saint-Jean"},{"name":"School of Rehabilitation, Faculty of Medecine and Health Sciences, CHU de Sherbrooke-Research Center, Universit\u00e9 de Sherbrooke, Sherbrooke, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Roos","sequence":"additional","affiliation":[{"name":"University Hospital D\u00fcsseldorf, Heinrich Heine University D\u00fcsseldorf"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain van","family":"Gool","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Impens","sequence":"additional","affiliation":[{"name":"VIB-UGent Center for Medical Biotechnology, VIB"},{"name":"Ghent University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Martens","sequence":"additional","affiliation":[{"name":"VIB-UGent Center for Medical Biotechnology, VIB"},{"name":"Ghent University"},{"name":"BioOrganic Mass Spectrometry Laboratory (LSMBO), IPHC UMR 7178, University of Strasbourg, CNRS, Strasbourg, France"},{"name":"Infrastructure Nationale de Prot\u00e9omique ProFI \u2212 UAR 2048, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanns","family":"Lochm\u00fcller","sequence":"additional","affiliation":[{"name":"The Ottawa Hospital"},{"name":"University of Ottawa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt","family":"Schoser","sequence":"additional","affiliation":[{"name":"Dep. of Neurology LMU Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Bassez","sequence":"additional","affiliation":[{"name":"Piti\u00e8-Salp\u00eatri\u00e8re Hospital, Assistance Publique H\u00f4pitaux de Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baziel GM","family":"van Engelen","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter AC","family":"\u2018t Hoen","sequence":"additional","affiliation":[{"name":"Radboud University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"OPTIMISTIC consortium, ReCognitION consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000011425"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-005-1298-8"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90154-5"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1546325"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1546326"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008056"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-018-0156-9"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30203-5"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3233\/JND-210634"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202013328"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30124-2"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2010.03.017"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15962-x"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-022-02591-y"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2011.02.003"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1980.tb01358.x"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-019-2285-3"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-015-0737-7"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2017.07.001"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/4.1.1"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/dds185"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-019-0638-x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31492-0"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkae1011"},{"key":"e_1_3_3_26_2","unstructured":"R Core Team. R: A Language and Environment for Statistical Computing."},{"key":"e_1_3_3_27_2","unstructured":"RStudio Team. RStudio: Integrated Development Environment for R."},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v035.b01"},{"key":"e_1_3_3_29_2","unstructured":"Wilke CO. cowplot: Streamlined Plot Theme and Plot Annotations for \u2018ggplot2\u2019."},{"key":"e_1_3_3_30_2","article-title":"Uniprot: the universal protein knowledgebase in 2025","volume":"53","author":"Consortium TU","year":"2025","unstructured":"Consortium TU, Bateman A, Martin M-J, et al. Uniprot: the universal protein knowledgebase in 2025. Nucleic Acids Res 2025; 53: D609\u2013D617.","journal-title":"Nucleic Acids Res"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.TIR119.001646"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"e_1_3_3_33_2","unstructured":"Barton K. MuMIn: Multi-Model Inference. R package version 1.46.0."},{"key":"e_1_3_3_34_2","unstructured":"Kassambara A. ggcorrplot: Visualization of a Correlation Matrix using \u2018ggplot2\u2019."},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v082.i13"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v059.i05"},{"key":"e_1_3_3_37_2","unstructured":"Kassambara A. ggpubr: \u2018ggplot2\u2019 Based Publication Ready Plots."},{"key":"e_1_3_3_38_2","first-page":"1","article-title":"Mice: multivariate imputation by chained equations in R","volume":"45","author":"van Buuren S","year":"2011","unstructured":"van Buuren S, Groothuis-Oudshoorn K. Mice: multivariate imputation by chained equations in R. J Stat Softw 2011; 45: 1\u201367.","journal-title":"J Stat Softw"},{"key":"e_1_3_3_39_2","unstructured":"Audigier V Resche-Rigon M. micemd: Multiple Imputation by Chained Equations with Multilevel Data."},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-21706-2"},{"key":"e_1_3_3_41_2","unstructured":"Canty A Ripley B. boot: Bootstrap R (S-Plus) Functions."},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v033.i01"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00344"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.12.028"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1198\/016214505000000637"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0051504"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-024-02754-6"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.3390\/cimb47050357"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2023.103489"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(03)00271-6"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105346"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1986.tb04639.x"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v11.i1.1"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.40219"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23063081"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/brv.12674"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-39663-3"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02546-3"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410120314"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11633-1"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddab364"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-020-0400-0"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-021-00895-4"},{"key":"e_1_3_3_64_2","first-page":"1","article-title":"The effects of exercise on complement system proteins in humans: a systematic scoping review","volume":"28","author":"Rothschild-Rodriguez D","year":"2022","unstructured":"Rothschild-Rodriguez D, Causer AJ, Brown FF, et al. The effects of exercise on complement system proteins in humans: a systematic scoping review. Exerc Immunol Rev 2022; 28: 1\u201335.","journal-title":"Exerc Immunol Rev"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2024.05.009"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.3233\/JND-230099"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI156125"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-022-11165-0"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.63.8.1149"}],"container-title":["Journal of Neuromuscular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/22143602251410443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/22143602251410443","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/22143602251410443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:07:54Z","timestamp":1788520074000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/22143602251410443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,16]]},"references-count":68,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/22143602251410443"],"URL":"https:\/\/doi.org\/10.1177\/22143602251410443","relation":{},"ISSN":["2214-3599","2214-3602"],"issn-type":[{"value":"2214-3599","type":"print"},{"value":"2214-3602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,16]]}}}