{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T06:26:16Z","timestamp":1777789576483,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Biomaterials &amp; Functional Materials"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aims to investigate the effect of coating time on the formation of hydroxyapatite (HA) coating layer on ZK60 substrate and understand the biodegradation behavior of the coated alloy for biodegradable implant applications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Biodegradable ZK60 alloy was coated by HA layer for different times of 0.5, 1, 2, and 4\u2009h by chemical conversion method. After coating, all the coated specimens were used for immersion test in Hanks\u2019 solution to understand the effect of coating time on the degradation behavior of the alloy. The degradation rate of the coated alloy was evaluated by Mg\n                      <jats:sup>2+<\/jats:sup>\n                      ion quantification and pH change during immersion test. The microstructure of the coating layer was examined by scanning electron microscope (SEM) equipped with an energy-dispersive X-ray spectroscopy (EDS) before and after immersion to understand the degradation behavior of the coated alloy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      HA coating layers were formed successfully on surface of ZK60 specimens after 0.5, 1, 2, and 4\u2009h with different microstructure. Optimal coating quality was observed at 1 or 2\u2009h, characterized by well-formed and uniform HA layers. However, extending the coating duration to 4\u2009h led to the formation of cracks within the HA layer, accompanied by Mg(OH)\n                      <jats:sub>2<\/jats:sub>\n                      . Specimens coated for 1 and 2\u2009h exhibited the lowest degradation rates, while specimens coated for 0.5 and 4\u2009h showed the highest degradation rates. Furthermore, analysis of degradation products revealed the predominance of calcium phosphates formed on the surface of specimens coated for 1 and 2\u2009h. Conversely, specimens coated for 0.5 and 4\u2009h exhibited Mg(OH)\n                      <jats:sub>2<\/jats:sub>\n                      as the primary degradation product, suggesting a less effective corrosion barrier under these conditions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The HA layer formed after 2\u2009h demonstrated as the most effective coating layer for enhancing the corrosion resistance of the ZK60 alloy for biomedical applications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/22808000241251564","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T06:09:53Z","timestamp":1719209393000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of coating time on the formation of coating layer and degradation behavior of hydroxyapatite coated ZK60 alloy"],"prefix":"10.1177","volume":"22","author":[{"given":"Le","family":"Van Hai","sequence":"first","affiliation":[{"name":"103 Military Hospital, Vietnam Military Medical University, Hanoi, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do","family":"Nhu Ngoc","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pham","family":"Mai Khanh","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Van Tuan","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vu","family":"Nhat Dinh","sequence":"additional","affiliation":[{"name":"103 Military Hospital, Vietnam Military Medical University, Hanoi, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1885-013X","authenticated-orcid":false,"given":"Nguyen","family":"Viet Nam","sequence":"additional","affiliation":[{"name":"Institute of Traumatology and Orthopedics, 108 Military Central Hospital, Hanoi, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,6,24]]},"reference":[{"key":"bibr1-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33542"},{"key":"bibr2-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-019-00170-y"},{"key":"bibr3-22808000241251564","doi-asserted-by":"publisher","DOI":"10.3390\/ma15031148"},{"key":"bibr4-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmrt.2023.02.037"},{"key":"bibr5-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.59"},{"key":"bibr6-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.jma.2021.06.024"},{"key":"bibr7-22808000241251564","doi-asserted-by":"publisher","DOI":"10.3390\/jfb14060324"},{"key":"bibr8-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtla.2023.101680"},{"key":"bibr9-22808000241251564","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph7041342"},{"key":"bibr10-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1007\/BF02783770"},{"key":"bibr11-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.mseb.2011.05.032"},{"key":"bibr12-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-010-4111-8"},{"key":"bibr13-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmst.2020.02.017"},{"key":"bibr14-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2016.12.002"},{"key":"bibr15-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.jma.2020.05.003"},{"key":"bibr16-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.electacta.2009.07.033"},{"key":"bibr17-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.surfcoat.2011.04.036"},{"key":"bibr18-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1080\/14686996.2020.1761237"},{"key":"bibr19-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1088\/1757-899X\/547\/1\/012004"},{"key":"bibr20-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1021\/ac60110a016"},{"key":"bibr21-22808000241251564","doi-asserted-by":"publisher","DOI":"10.3390\/ma12213474"},{"key":"bibr22-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2011.04.087"},{"key":"bibr23-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1149\/2.0171504jes"},{"key":"bibr24-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/0010-938X(85)90070-8"},{"key":"bibr25-22808000241251564","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3390\/coatings8070239","volume":"8","author":"Wu G","year":"2018","journal-title":"Coatings"},{"key":"bibr26-22808000241251564","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.surfcoat.2012.11.025","volume":"220","author":"Li Y","year":"2013","journal-title":"Surf Coat Technol"},{"key":"bibr27-22808000241251564","first-page":"4199","volume":"33","author":"Seitz JM","year":"2013","journal-title":"Mater Sci Eng C"},{"key":"bibr28-22808000241251564","first-page":"357","volume":"178","author":"Mao L","year":"2013","journal-title":"Mater Sci Eng B"},{"key":"bibr29-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.surfcoat.2022.128639"},{"key":"bibr30-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.11.022"},{"key":"bibr31-22808000241251564","volume":"19","author":"Hanh L","year":"2021","journal-title":"J Appl Biomater Funct Mater"},{"key":"bibr32-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.10.021"},{"key":"bibr33-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/j.cossms.2009.04.001"},{"key":"bibr34-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1557\/JMR.1998.0015"},{"key":"bibr35-22808000241251564","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/1097-4636(20000905)51:3<475::AID-JBM23>3.0.CO;2-9","volume":"51","author":"Webster TJ","year":"2000","journal-title":"J Biomed Mater Res"},{"key":"bibr36-22808000241251564","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-819586-4.00005-6"},{"key":"bibr37-22808000241251564","volume":"17","author":"Yousefi AM.","year":"2019","journal-title":"J Appl Biomater Funct Mater"}],"container-title":["Journal of Applied Biomaterials &amp; Functional Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/22808000241251564","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/22808000241251564","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/22808000241251564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:57:21Z","timestamp":1777492641000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/22808000241251564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":37,"alternative-id":["10.1177\/22808000241251564"],"URL":"https:\/\/doi.org\/10.1177\/22808000241251564","relation":{},"ISSN":["2280-8000","2280-8000"],"issn-type":[{"value":"2280-8000","type":"print"},{"value":"2280-8000","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"22808000241251564"}}