{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:41:29Z","timestamp":1777880489839,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"},{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p>Infection caused by Brucella following total joint arthroplasty is very rare. We present 2 cases of brucellar infection following total hip arthroplasty (THA). A 66-year-old woman who had prolonged contact with cattle presented with pain at the thigh and groin areas. The patient had undergone an uncemented THA for a hip fracture 3 years previously. Cultures of articular liquid were positive for Brucella abortus. The implant was loosened and was managed with a 2-stage re-implantation. A 71-year-old man presented with painless suppuration of the hip joint through the scar from previous surgeries. Radiography demonstrated a well-integrated THA. When postoperative cultures were found positive for Brucella melitensis, antibiotic treatment of rifampicin 900 mg, streptomycin 1 g, and doxycycline 200 mg daily were prescribed. At 5.5-year and 5-year follow-up, respectively, both patients were asymptomatic and free of infection with well-integrated implants. As the Brucella pathogen is highly susceptible to antibiotics, standard 2-stage revision arthroplasty for loosened implant or debridement and antibiotic treatment for well-fixed implant should suffice.<\/jats:p>","DOI":"10.1177\/230949900601400122","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T17:14:58Z","timestamp":1475601298000},"page":"99-103","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Total Hip Arthroplasty Infected by\n                    <i>Brucella<\/i>\n                    : A Report of Two Cases"],"prefix":"10.1177","volume":"14","author":[{"given":"MA","family":"Ruiz-Iban","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Crespo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Diaz-Peletier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AM","family":"Rozado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Lopez-Pardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,4,1]]},"reference":[{"key":"bibr1-230949900601400122","first-page":"111","volume":"48","author":"Hanssen AD","year":"1999","journal-title":"Instr Course Lect"},{"key":"bibr2-230949900601400122","first-page":"223","volume":"52","author":"Salvati EA","year":"2003","journal-title":"Instr Course Lect"},{"key":"bibr3-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200403000-00005"},{"key":"bibr4-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/9.3.531"},{"key":"bibr5-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.1.63"},{"key":"bibr6-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1086\/368084"},{"key":"bibr7-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200403000-00010"},{"key":"bibr8-230949900601400122","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S0025-7753(02)73409-X","volume":"119","author":"Ariza J","year":"2002","journal-title":"Med Clin (Barc)"},{"key":"bibr9-230949900601400122","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199301000-00010"},{"key":"bibr10-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1054\/arth.2002.30284"},{"key":"bibr11-230949900601400122","doi-asserted-by":"publisher","DOI":"10.3928\/0147-7447-19830201-09"},{"key":"bibr12-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1080\/00365540310017456"},{"key":"bibr13-230949900601400122","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00003086-199106000-00028","volume":"267","author":"Agarwal S","year":"1991","journal-title":"Clin Orthop Relat Res"},{"key":"bibr14-230949900601400122","first-page":"283","volume":"26","author":"Malizos KN","year":"1997","journal-title":"Am J Orthop"},{"key":"bibr15-230949900601400122","doi-asserted-by":"publisher","DOI":"10.1007\/BF01700416"}],"container-title":["Journal of Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/230949900601400122","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/230949900601400122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:13:00Z","timestamp":1777594380000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/230949900601400122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1177\/230949900601400122"],"URL":"https:\/\/doi.org\/10.1177\/230949900601400122","relation":{},"ISSN":["1022-5536","2309-4990"],"issn-type":[{"value":"1022-5536","type":"print"},{"value":"2309-4990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}