{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T07:08:49Z","timestamp":1789715329209,"version":"4.0.1"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To review records of 8 patients with telangiectatic osteosarcoma (TOS) and determine whether pathologic fractures correlate with recurrence and survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Records of 4 men and 4 women aged 17 to 44 (mean, 28) years treated for TOS were reviewed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Of the 8 patients, 4 developed a pathologic fracture and 4 did not. In each group, 2 patients underwent limb salvage surgery and 2 underwent amputation. All patients received neoadjuvant and adjuvant chemotherapy with a combination of at least 2 of the following drugs: doxorubicin, methotrexate, cisplatin, and vincristin. After a mean follow-up of 5.6 (range, 2\u201316) years, all 4 patients with a pathologic fracture and 2 of the 4 patients without a pathologic fracture were still alive and disease-free. For the remaining patients, one died after 31 months from progression of a lung metastasis, and the other was alive with the disease and had had 2 recurrences, a lung metastasis, and an infection with Klebsiella oxytoca that eventually led to an amputation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>The presence of a pathologic fracture in patients with TOS was not associated with worse outcome in terms of recurrence and survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/230949901302100124","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T17:13:55Z","timestamp":1475601235000},"page":"96-99","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Telangiectatic Osteosarcoma"],"prefix":"10.1177","volume":"21","author":[{"given":"Jordi","family":"Colomina","sequence":"first","affiliation":[{"name":"Department of Oncologic Orthopaedic Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Peiro","sequence":"additional","affiliation":[{"name":"Department of Oncologic Orthopaedic Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Trullols","sequence":"additional","affiliation":[{"name":"Department of Oncologic Orthopaedic Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isidre","family":"Gracia","sequence":"additional","affiliation":[{"name":"Department of Oncologic Orthopaedic Surgery, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,12,4]]},"reference":[{"key":"bibr1-230949901302100124","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197410)34:4<1150::AID-CNCR2820340426>3.0.CO;2-S"},{"key":"bibr2-230949901302100124","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197612)38:6<2538::AID-CNCR2820380643>3.0.CO;2-1"},{"key":"bibr3-230949901302100124","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22574"},{"key":"bibr4-230949901302100124","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/00003086-198606000-00030","volume":"207","author":"Rosen G","year":"1986","journal-title":"Clin Orthop Relat 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