{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T14:10:35Z","timestamp":1793369435681,"version":"4.5.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose.<\/jats:title>\n                    <jats:p>To review the records of 50 children who underwent open joint washout for septic arthritis with (n=25) or without (n=25) preoperative antibiotics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Records of 50 children who underwent open joint washout for presumed septic arthritis with (n=25) or without (n=25) preoperative antibiotics were reviewed. 17 boys and 8 girls aged 3 weeks to 16 years (median, 1.5 years) who were prescribed preoperative antibiotics before joint washout were compared with 12 boys and 13 girls aged one month to 14 years (median, 2 years) who were not. Following arthrotomy and washout, all patients were commenced on high-dose intravenous antibiotics. Patients were followed up for 6 to 18 months until asymptomatic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Patients who were referred from places other than our emergency department were twice as likely to have been prescribed preoperative antibiotics (p=0.0032). Patients prescribed preoperative antibiotics had a longer median (range) time from symptom onset to joint washout (8 [2\u201323] vs. 4 [1\u201329] days, p=0.05) and a higher mean erythrocyte sedimentation rate (93.1 vs. 54.3 mm\/h, p=0.023) at presentation. Nonetheless, the 2 groups were comparable for weight bearing status, fever, and positive culture, as well as the mean (range) duration of antibiotic treatment (4.9 [4\u20137] vs. 4.7 [1\u20138] weeks, p=0.586).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>Preoperative antibiotics should be avoided in the management of septic arthritis in children. Their prescription delays diagnosis and definitive surgery, and leads to additional washouts and complications. A high index of suspicion and expedite referral to a specialist paediatric orthopaedic unit is needed if septic arthritis is suspected.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/230949901502300119","type":"journal-article","created":{"date-parts":[[2016,10,4]],"date-time":"2016-10-04T17:13:55Z","timestamp":1475601235000},"page":"80-83","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Preoperative Antibiotics for Septic Arthritis in Children: Delay in Diagnosis"],"prefix":"10.1177","volume":"23","author":[{"given":"Simon BM","family":"MacLean","sequence":"first","affiliation":[{"name":"Birmingham Children's Hospital, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Timmis","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Evans","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Lawniczak","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Nijran","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Bache","sequence":"additional","affiliation":[{"name":"Birmingham Children's Hospital, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,4,1]]},"reference":[{"key":"bibr1-230949901502300119","first-page":"99","volume-title":"Fundamentals of pediatric orthopaedics","author":"Staheli LT","year":"2008","edition":"4"},{"key":"bibr2-230949901502300119","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200606000-00012"},{"key":"bibr3-230949901502300119","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200405000-00011"},{"key":"bibr4-230949901502300119","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199912000-00002"},{"key":"bibr5-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02305-07"},{"key":"bibr6-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2008.07.001"},{"key":"bibr7-230949901502300119","unstructured":"British Society for Children's Orthopaedic Surgery. The management of acute bone and joint infection in childhood. A guide to good practice. Available from http:\/\/bscos.org.uk\/resources\/Downloads\/Blue-Book-Infection.pdf."},{"key":"bibr8-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.65B3.6841388"},{"key":"bibr9-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199008000-00036"},{"key":"bibr10-230949901502300119","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200306000-00002"},{"key":"bibr11-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-199802000-00015"},{"key":"bibr12-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.68B4.3733835"},{"key":"bibr13-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2011-300462"},{"key":"bibr14-230949901502300119","first-page":"388","volume":"68","author":"Faraj AA","year":"2002","journal-title":"Acta Orthop Belg"},{"key":"bibr15-230949901502300119","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2006.12.001"}],"container-title":["Journal of Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/230949901502300119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/230949901502300119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:20:55Z","timestamp":1777594855000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/230949901502300119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1177\/230949901502300119"],"URL":"https:\/\/doi.org\/10.1177\/230949901502300119","relation":{},"ISSN":["1022-5536","2309-4990"],"issn-type":[{"value":"1022-5536","type":"print"},{"value":"2309-4990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4]]}}}