{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:46:37Z","timestamp":1777880797663,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Various modes of therapy have been directed at breaking the vicious cycle at early stage of synovitis in haemophilia patients. This study was planned to assess the short-term clinico-radiological outcome of chronic knee synovitis among haemophilia A patients post phosphorus-32 (P-32) radiosynoviorthesis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>P-32 samarium radiocolloid was injected into the knee and patients were followed up at 1 and 3 months, respectively. Clinical outcomes was assessed using Tegner Lysholm scores (TLSs), Modified Knee Society Clinical Rating System (MKSS) score and circumference of the knee joint. The radiological outcomes were assessed using X-ray, ultrasonography and bone scan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among the fifteen haemophilia A patients studied, there was statistically significant difference in TLS ( \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      (2) = 27.887 and p value &lt; 0.001), MKSS scores ( \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      (2) = 27.745 and p &lt; 0.001) and circumference of the knee joint ( \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      (2) = 21.333 and p &lt; 0.001) at preoperatively, 1- and 3-month follow-up. There were no changes noted in follow-up X-rays compared with the preoperative X-ray. Ultrasonography showed that clinical improvement was more in suprapatellar and medial parapatellar regions in the last 2 months compared to the first month of follow-up. Post P-32 bone scan showed marked decrease in uptake in the affected knee joint suggestive of radio ablation of synovial tissue.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>P-32 radiosynoviorthesis done for chronic synovitis among haemophilia A patients showed significant improvement in both clinical and radiological parameters. Ultrasonography can be utilized as non-invasive radiological modality for follow-up of P32 response for knee joint.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2309499016684500","type":"journal-article","created":{"date-parts":[[2017,2,14]],"date-time":"2017-02-14T04:23:21Z","timestamp":1487046201000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Short-term clinico-radiological outcome of chronic knee synovitis among haemophilia A patients post phosphorus-32 radiosynoviorthesis"],"prefix":"10.1177","volume":"25","author":[{"given":"Prasanna","family":"TY","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagadish","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nataraj","family":"AR","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, ESIC-MC & PGIMSR, Rajajinagar, Bengaluru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhanapathi","family":"Halanaik","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harshith","family":"Kramadhari","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,2,13]]},"reference":[{"key":"bibr1-2309499016684500","volume-title":"Robbins pathological basis of disease","author":"Kumar V","year":"2009"},{"key":"bibr2-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2001.00109.x"},{"key":"bibr3-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830270107"},{"key":"bibr4-2309499016684500","first-page":"1113","volume":"20","author":"Deutch E","year":"1993","journal-title":"Eur J Nucl Med"},{"key":"bibr5-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1007\/BF00808408"},{"key":"bibr6-2309499016684500","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200401000-00008"},{"key":"bibr7-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198509000-00007"},{"key":"bibr8-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198911000-00004"},{"key":"bibr9-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2012.02922.x"},{"key":"bibr10-2309499016684500","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-2998(97)80009-8"},{"key":"bibr11-2309499016684500","first-page":"254","volume":"11","author":"De La Corte-Rodriguez H","year":"2013","journal-title":"Blood Transfus"},{"key":"bibr12-2309499016684500","doi-asserted-by":"publisher","DOI":"10.2349\/biij.3.4.e45"},{"key":"bibr13-2309499016684500","doi-asserted-by":"publisher","DOI":"10.4274\/MIRT.25"},{"key":"bibr14-2309499016684500","first-page":"48","volume":"1","author":"Schneider P","year":"2005","journal-title":"J Nucl Med"}],"container-title":["Journal of Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2309499016684500","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2309499016684500","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2309499016684500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:22:43Z","timestamp":1777594963000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2309499016684500"}},"subtitle":["Single group prospective study"],"short-title":[],"issued":{"date-parts":[[2017,1,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1,1]]}},"alternative-id":["10.1177\/2309499016684500"],"URL":"https:\/\/doi.org\/10.1177\/2309499016684500","relation":{},"ISSN":["1022-5536","2309-4990"],"issn-type":[{"value":"1022-5536","type":"print"},{"value":"2309-4990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,1]]},"article-number":"2309499016684500"}}