{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T17:47:54Z","timestamp":1792259274639,"version":"4.4.0"},"reference-count":80,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:p>Due to accurate preoperative imaging techniques, early diagnosis and effective chemotherapy, many tumors arising in the metaphyseo-diaphyseal regions of long bones can be segmentally resected with joint preservation. The intercalary resection of malignant bone tumor results in a bone defect which can represent a challenging reconstructive problem. The most commonly used surgical reconstructive options for these defects include biologic reconstructions such as allografts, vascularized fibular grafts, autogenous extracorporeally devitalized tumor bearing bone graft, combination of allografts or devitalized autografts with vascularized fibular grafts, segmental bone transport, or induced membrane technique. Nonbiologic reconstructions, on the other hand, use intercalary endoprostheses. Every patient should be carefully evaluated and the reconstructive option should be individually selected. The aim of this article is to discuss the surgical options of reconstruction of bone defects after intercalary resection of malignant bone tumors with reviewing of their indications, advantages, disadvantages and complications.<\/jats:p>","DOI":"10.1177\/2309499019832970","type":"journal-article","created":{"date-parts":[[2019,3,17]],"date-time":"2019-03-17T23:15:38Z","timestamp":1552864538000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":84,"title":["Reconstruction of intercalary bone defect after resection of malignant bone tumor"],"prefix":"10.1177","volume":"27","author":[{"given":"Karem M","family":"Zekry","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan"},{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, Minya University, Minya, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4071-5620","authenticated-orcid":false,"given":"Akihiko","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Zein AA","family":"Alkhooly","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, Minya University, Minya, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Saleh","family":"Abd-Elfattah","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, Minya University, Minya, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Nady Saleh","family":"Elsaid","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, Minya University, Minya, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel Refaat","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, Alexandria University, Alexandria, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Tsuchiya","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,3,17]]},"reference":[{"key":"bibr1-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.11.010"},{"key":"bibr2-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-017-1985-x"},{"key":"bibr3-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-017-3446-x"},{"key":"bibr4-2309499019832970","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199701000-00010"},{"key":"bibr5-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-011-1952-5"},{"key":"bibr6-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199603000-00011"},{"key":"bibr7-2309499019832970","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.M.00655"},{"key":"bibr8-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.74B6.1447252"},{"key":"bibr9-2309499019832970","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.3928\/0147-7447-19921001-05","volume":"15","author":"Mankin HJ","year":"1992","journal-title":"Orthopedics"},{"key":"bibr10-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000141652.93178.10"},{"key":"bibr11-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.94B6.28680"},{"key":"bibr12-2309499019832970","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199311000-00011"},{"key":"bibr13-2309499019832970","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199405000-00005"},{"key":"bibr14-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200101000-00014"},{"key":"bibr15-2309499019832970","first-page":"85","volume":"140","author":"Weiland AJ","year":"1977","journal-title":"Johns Hopkins Med J"},{"key":"bibr16-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000122213.82011.C5"},{"key":"bibr17-2309499019832970","first-page":"86","volume":"8","author":"Bae DS","year":"2006","journal-title":"Orthop J Harv Med School"},{"key":"bibr18-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-864839"},{"key":"bibr19-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01460-2"},{"key":"bibr20-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000181736.85276.78"},{"key":"bibr21-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000252306.72483.9b"},{"key":"bibr22-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-014-0632-1"},{"key":"bibr23-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.82B7.10332"},{"key":"bibr24-2309499019832970","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199602000-00006"},{"key":"bibr25-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-19888"},{"key":"bibr26-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/BF02620523"},{"key":"bibr27-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2006.10.008"},{"key":"bibr28-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000189203.38204.d5"},{"key":"bibr29-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/160295"},{"key":"bibr30-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1267381"},{"key":"bibr31-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000227682.71527.2b"},{"key":"bibr32-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-823106"},{"key":"bibr33-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1002\/micr.20668"},{"key":"bibr34-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21620"},{"key":"bibr35-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B5.15491"},{"key":"bibr36-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.79B3.0790403"},{"key":"bibr37-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.78B2.0780264"},{"key":"bibr38-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.84B8.13330"},{"key":"bibr39-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199809000-00025"},{"key":"bibr40-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s004020000241"},{"key":"bibr41-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199802000-00028"},{"key":"bibr42-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7091-6885-1_17"},{"key":"bibr43-2309499019832970","first-page":"RA107","volume":"14","author":"Nishida J","year":"2008","journal-title":"Med Sci Monit"},{"key":"bibr44-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(05)80269-0"},{"key":"bibr45-2309499019832970","first-page":"S1840","volume":"74","author":"Ahmed AR","year":"2000","journal-title":"J Jpn Orthop Assoc"},{"key":"bibr46-2309499019832970","first-page":"227","volume":"311","author":"Rong Y","year":"1995","journal-title":"Clin Orthop Relat Res"},{"key":"bibr47-2309499019832970","first-page":"1015","volume":"4","author":"Spira E","year":"1968","journal-title":"Isr J Med Sci"},{"key":"bibr48-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-012-1715-2"},{"key":"bibr49-2309499019832970","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200710000-00001"},{"key":"bibr50-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.89B3.18508"},{"key":"bibr51-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.94B9.29164"},{"key":"bibr52-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B6.15950"},{"key":"bibr53-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.94B7.28916"},{"key":"bibr54-2309499019832970","first-page":"137","volume":"181","author":"Johnston JO","year":"1983","journal-title":"Clin Orthop Relat Res"},{"key":"bibr55-2309499019832970","first-page":"115","volume":"1","author":"Shimozaki E","year":"1993","journal-title":"J Orthop Surg"},{"key":"bibr56-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-10-105"},{"key":"bibr57-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s002640050272"},{"key":"bibr58-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000205876.05093.80"},{"key":"bibr59-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200402000-00042"},{"key":"bibr60-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/BLO.0b013e31802e7ec8"},{"key":"bibr61-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200109000-00029"},{"key":"bibr62-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1177\/00220345710500060601"},{"key":"bibr63-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23727"},{"key":"bibr64-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s10776-002-0626-3"},{"key":"bibr65-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.96B4.32629"},{"key":"bibr66-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/j.cryobiol.2011.09.001"},{"key":"bibr67-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B2.15325"},{"key":"bibr68-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-010-1458-0"},{"key":"bibr69-2309499019832970","doi-asserted-by":"crossref","unstructured":"Abdelaal AHK, Yamamoto N, Hayashi K, Epiphyseal sparing and reconstruction by frozen bone autograft after malignant bone tumor resection in children. Sarcoma 2015. doi: http:\/\/dx.doi.org\/10.1155\/2015\/892141.","DOI":"10.1155\/2015\/892141"},{"key":"bibr70-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21893"},{"key":"bibr71-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.92B6.23449"},{"key":"bibr72-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-004-0614-6"},{"key":"bibr73-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.88B11.18038"},{"key":"bibr74-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.78B4.0780652"},{"key":"bibr75-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1177\/147323000903700432"},{"key":"bibr76-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-012-2635-6"},{"key":"bibr77-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2009.07.011"},{"key":"bibr78-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2010.02.010"},{"key":"bibr79-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-015-0694-3"},{"key":"bibr80-2309499019832970","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-013-1678-9"}],"container-title":["Journal of Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2309499019832970","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2309499019832970","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2309499019832970","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:26:31Z","timestamp":1777595191000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2309499019832970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":80,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1,1]]}},"alternative-id":["10.1177\/2309499019832970"],"URL":"https:\/\/doi.org\/10.1177\/2309499019832970","relation":{},"ISSN":["1022-5536","2309-4990"],"issn-type":[{"value":"1022-5536","type":"print"},{"value":"2309-4990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,1]]},"article-number":"2309499019832970"}}