{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T05:56:58Z","timestamp":1788328618158,"version":"build-2803163510"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2019,9,1]]},"abstract":"<jats:p>We describe a modified surgical technique developed to enhance the classical irrigation and debridement procedure to improve the possibilities of retaining an infected total knee arthroplasty. This technique, debridement antibiotic pearls and retention of the implant (DAPRI), aims to remove the intra-articular biofilm allowing a higher and prolonged local antibiotic concentration using calcium sulfate beads. The combination of three different surgical techniques (methylene blue staining, argon beam electrical stimulation, and chlorhexidine gluconate brushing) might enhance the identification, disruption, and finally removal of the bacterial biofilm, which is the main responsible of antibiotics and antibodies resistance. The DAPRI technique might represent a safe and more conservative treatment for acute and early hematogenous periprosthetic joint infection.<\/jats:p>","DOI":"10.1177\/2309499019874413","type":"journal-article","created":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T23:13:58Z","timestamp":1569453238000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":35,"title":["Debridement, antibiotic pearls, and retention of the implant (DAPRI): A modified technique for implant retention in total knee arthroplasty PJI treatment"],"prefix":"10.1177","volume":"27","author":[{"given":"Filippo","family":"Calanna","sequence":"first","affiliation":[{"name":"Istituto Ortopedico Gaetano Pini, Division of Orthopaedic Surgery, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foster","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Stanford University, 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