{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:05:50Z","timestamp":1790129150687,"version":"4.0.1"},"reference-count":43,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Post-Doctor Research Project, West China Hospital, Sichuan University","award":["2018HXBH002"],"award-info":[{"award-number":["2018HXBH002"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2020,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>Cervical sagittal balance plays important roles in transmitting the load of the head and maintaining global spinal balance. This study aimed to identify the association of cervical sagittal alignment with adjacent segment degeneration (ASD) and heterotopic ossification (HO) after Prestige-LP cervical disc replacement (CDR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We enrolled 132 patients who underwent one-level Prestige-LP CDR with 2\u201310 years of follow-up. Cervical sagittal alignment parameters, including the degree of C2\u2013C7 lordosis (CL), functional spinal unit angle (FSUA), sagittal vertical axis (SVA),, and T1 slope (T1s), were measured. ASD and HO were evaluated at the last follow-up. Unpaired t tests and logistic regression analysis were used to identify the associations of cervical sagittal alignment with ASD and HO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We found that patients who developed ASD showed significantly lower FSUA (2.1\u00b0 vs. \u22121.4\u00b0, p &lt; 0.001) and T1s values (28.4\u00b0 vs. 25.5\u00b0, p = 0.029) after surgery. Similarly, the postoperative CL was significantly better in patients without ASD or HO (18.0\u00b0 vs. 14.4\u00b0, p = 0.043). The decrease in the T1s at the last follow-up was significantly larger in the patients with ASD (\u221211.0\u00b0 vs. \u22123.2\u00b0, p = 0.003), HO (\u22126.7\u00b0 vs. \u22122.7\u00b0, p = 0.050), and ASD or HO (\u22127.0\u00b0 vs. \u22120.8\u00b0, p &lt; 0.001) than in those without ASD or HO. Multivariate logistic regression analysis showed that both the FSUA and T1s are associated with ASD and that the degree of CL is associated with postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The results imply that maintaining cervical sagittal alignment after Prestige-LP CDR is important.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2309499020968295","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T06:08:00Z","timestamp":1604988480000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Association of cervical sagittal alignment with adjacent segment degeneration and heterotopic ossification following cervical disc replacement with Prestige-LP disc"],"prefix":"10.1177","volume":"28","author":[{"given":"Xiaofei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6938-8774","authenticated-orcid":false,"given":"Hao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beiyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Operation Room, West China Hospital, Sichuan University, Sichuan, China"},{"name":"West China School of Nursing, Sichuan University, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,10]]},"reference":[{"key":"bibr1-2309499020968295","doi-asserted-by":"publisher","DOI":"10.3171\/2013.4.SPINE12838"},{"key":"bibr2-2309499020968295","first-page":"13","volume":"100","author":"Ferch RD","year":"2004","journal-title":"J 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