{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:54:34Z","timestamp":1777672474082,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2014,7,1]]},"abstract":"<jats:p>In the present case, a 49-year-old white female presented to the clinic with a 2-month history of nausea, vomiting, and right upper quadrant pain. On examination a 3-cm mass on the right anterior scalene muscle was noted. A computed tomography scan was performed revealing a 8.7 \u00d7 7.7 \u00d7 6.1 cm retroperitoneal mass with possible invasion of the inferior vena cava and right renal and left common iliac veins. An excisional biopsy was performed with pathology compatible with spindle cell sarcoma. The patient was then sent for follow-up at the sarcoma clinic as an outpatient. However, before chemotherapy was to be started the patient would be admitted to the hospital with progressively worse nausea and vomiting. At that time the patient\u2019s lab work showed lactic acidosis, acute renal failure, hyperuricemia, hyperphosphatemia, and hypocalcemia, which met the Cairo\u2013Bishop criteria for tumor lysis syndrome (TLS). The patient was admitted to the intensive care unit and kidney dialysis initiated. The patient would become progressively obtunded at which time the family opted for hospice care. The patient eventually succumbed peacefully 3 days after her last admission. In this case report, we briefly review the literature on TLS in solid tumors, and we present a rare case of spontaneous TLS in a retroperitoneal sarcoma.<\/jats:p>","DOI":"10.1177\/2324709614542340","type":"journal-article","created":{"date-parts":[[2014,7,4]],"date-time":"2014-07-04T23:17:00Z","timestamp":1404515820000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Tumor Lysis Syndrome in a Retroperitoneal Sarcoma"],"prefix":"10.1177","volume":"2","author":[{"given":"Yousef","family":"Zakharia","sequence":"first","affiliation":[{"name":"Georgia Regents University, Augusta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Mansour","sequence":"additional","affiliation":[{"name":"Georgia Regents University, Augusta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinivasa","family":"Vasireddi","sequence":"additional","affiliation":[{"name":"Michigan State University, East Lansing, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kais","family":"Zakharia","sequence":"additional","affiliation":[{"name":"Michigan State University, East Lansing, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduard","family":"Fatakhov","sequence":"additional","affiliation":[{"name":"Georgia Regents University, Augusta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Koch","sequence":"additional","affiliation":[{"name":"Georgia Regents University, Augusta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borys","family":"Hrinczenko","sequence":"additional","affiliation":[{"name":"Michigan State University, East Lansing, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,9,22]]},"reference":[{"key":"bibr1-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6174.1320-a"},{"key":"bibr2-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05094.x"},{"key":"bibr3-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1159\/000324791"},{"key":"bibr4-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199502000-00015"},{"key":"bibr5-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-002-0556-x"},{"key":"bibr6-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/468452"},{"key":"bibr7-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1007\/s10585-010-9335-y"},{"key":"bibr8-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.10.2998"},{"key":"bibr9-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1965.03090010007001"},{"key":"bibr10-2324709614542340","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.15.0177"},{"key":"bibr11-2324709614542340","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.12327"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709614542340","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2324709614542340","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709614542340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:05:04Z","timestamp":1777449904000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2324709614542340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,1]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,7,1]]}},"alternative-id":["10.1177\/2324709614542340"],"URL":"https:\/\/doi.org\/10.1177\/2324709614542340","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,1]]},"article-number":"2324709614542340"}}