{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:54:42Z","timestamp":1777672482251,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2014,7,1]]},"abstract":"<jats:p>Objective. We present the clinical, biochemical, and imaging findings of a woman with vitamin D deficiency and severe osteomalacia related to intravenous heroin addiction. Results. A 54-year-old woman with a medical history significant for long-standing heroin abuse presented with complaints of bone pain, muscle cramping, and a left hip ulcer. She had been bed bound for approximately 1 year secondary to pain of uncertain etiology, and her husband was bringing her both food and drugs. She was admitted to the hospital for debridement of a right ischial ulcer. Further workup revealed osteomyelitis of the left hip and severe vitamin D deficiency. Radiologic evaluation demonstrated diffuse osteopenia with pseudofractures, as well as true fractures. Conclusion. This is the first case reported in the English literature of advanced osteomalacia resulting from a debilitating narcotic dependency. Vitamin D deficiency should be considered in patients with poor nutrition and prolonged sunlight deprivation from any cause.<\/jats:p>","DOI":"10.1177\/2324709614548797","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T11:25:25Z","timestamp":1409829925000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Severe Osteomalacia Related to Long-Term Intravenous Drug Abuse"],"prefix":"10.1177","volume":"2","author":[{"given":"Leslie","family":"Gamache","sequence":"first","affiliation":[{"name":"Health One, Denver Endocrinology, Denver, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark R.","family":"Burge","sequence":"additional","affiliation":[{"name":"University of New Mexico Health Sciences Center, Albuquerque, NM, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,9,22]]},"reference":[{"key":"bibr1-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1210\/edrv.22.4.0437"},{"key":"bibr2-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803193381201"},{"key":"bibr3-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0746"},{"key":"bibr4-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/76.1.187"},{"key":"bibr5-2324709614548797","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0033-8389(22)02681-1","volume":"29","author":"Pitt MJ","year":"1991","journal-title":"Radiol Clin North Am"},{"key":"bibr6-2324709614548797","first-page":"1693","volume":"79","author":"Garnero P","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"bibr7-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1673S"},{"key":"bibr8-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1706S"},{"key":"bibr9-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803193381209"},{"key":"bibr10-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2011.06.021"},{"key":"bibr11-2324709614548797","doi-asserted-by":"publisher","DOI":"10.1556\/APhysiol.97.2010.4.8"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709614548797","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2324709614548797","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709614548797","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:05:05Z","timestamp":1777449905000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2324709614548797"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,1]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,7,1]]}},"alternative-id":["10.1177\/2324709614548797"],"URL":"https:\/\/doi.org\/10.1177\/2324709614548797","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,1]]},"article-number":"2324709614548797"}}