{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:32:14Z","timestamp":1777671134749,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>This report presents a case of tacrolimus cardiotoxicity in an adult patient who received tacrolimus immunosuppression for orthotopic liver transplant (OLT). Tacrolimus-associated cardiotoxicity has been described in the literature, however this is the first case to document the development of a dilated cardiomyopathy in a patient shortly after initiating tacrolimus therapy post transplant. With the growing use of tacrolimus in transplant medicine, this case report expands the literature of tacrolimus cardiotoxicity and can aid clinicians in the evaluation and management of patients exposed to this form of immunosuppression.<\/jats:p>","DOI":"10.1177\/2324709617706087","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T03:39:42Z","timestamp":1493264382000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Tacrolimus-Associated Dilated Cardiomyopathy in Adult Patient After Orthotopic Liver Transplant"],"prefix":"10.1177","volume":"5","author":[{"given":"Jennifer","family":"McLeod","sequence":"first","affiliation":[{"name":"University of Southern California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Wu","sequence":"additional","affiliation":[{"name":"University of Southern California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luanda","family":"Grazette","sequence":"additional","affiliation":[{"name":"University of Southern California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Sarcon","sequence":"additional","affiliation":[{"name":"University of Southern California, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,4,27]]},"reference":[{"key":"bibr1-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00630-6"},{"key":"bibr2-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2000.tb01004.x"},{"key":"bibr3-2324709617706087","first-page":"3071","volume":"23","author":"Japanese FK506 Study Group","year":"1991","journal-title":"Transplant Proc"},{"key":"bibr4-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)90011-X"},{"key":"bibr5-2324709617706087","unstructured":"Uemoto S, Inomata Y, Egawa H, Effects of tacrolimus on cardiac function after living related liver transplantation in paediatric patients. Paper presented at: 15th Annual Meeting of the American Society of Transplant Physicians; May 26-30, 1996; Dallas, TX."},{"key":"bibr6-2324709617706087","first-page":"2250","volume":"28","author":"Baruch Y","year":"1996","journal-title":"Transplant Proc"},{"key":"bibr7-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200209270-00015"},{"key":"bibr8-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1097\/00007691-199512000-00011"},{"key":"bibr9-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199709150-00020"},{"key":"bibr10-2324709617706087","first-page":"855","volume":"26","author":"Nomoto S","year":"1994","journal-title":"Transplant Proc"},{"key":"bibr11-2324709617706087","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2001.00052.x"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709617706087","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2324709617706087","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709617706087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:59:20Z","timestamp":1777449560000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2324709617706087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1177\/2324709617706087"],"URL":"https:\/\/doi.org\/10.1177\/2324709617706087","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]},"article-number":"2324709617706087"}}