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She was on oral prednisone and was recently started on canakinumab (interleukin-1 antagonist) for joint pain and rash of AOSD. Echocardiogram showed severely dilated right ventricle, dilated pulmonary artery, moderately reduced right ventricular systolic function, but with normal left ventricular systolic function. Computed tomography with contrast ruled out pulmonary embolism. Blood tests ruled out other rheumatologic diseases. The patient was diagnosed with right-sided heart failure likely secondary to AOSD. Right heart catheterization was needed but could not be performed because of severely dilated pulmonary artery. The patient was transferred to a higher center for further management and possible cardiopulmonary transplant.<\/jats:p>","DOI":"10.1177\/2324709618757260","type":"journal-article","created":{"date-parts":[[2018,2,14]],"date-time":"2018-02-14T00:36:53Z","timestamp":1518568613000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Severe Pulmonary Hypertension Due to Adult-Onset Still\u2019s Disease"],"prefix":"10.1177","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6245-3115","authenticated-orcid":false,"given":"Ankur","family":"Sinha","sequence":"first","affiliation":[{"name":"Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravikaran","family":"Patti","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paurush","family":"Ambesh","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chukwudi","family":"Obiagwu","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Namrita","family":"Malhan","sequence":"additional","affiliation":[{"name":"Sri Aurobindo Institute of Medical Sciences, Indore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kabu","family":"Chawla","sequence":"additional","affiliation":[{"name":"Maimonides Medical Center, Brooklyn, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,2,13]]},"reference":[{"key":"bibr1-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2487-4."},{"key":"bibr2-2324709618757260","first-page":"424","volume":"19","author":"Yamaguchi M","year":"1992","journal-title":"J Rheumatol"},{"key":"bibr3-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1136\/ard.51.5.683"},{"key":"bibr4-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2016.06.007."},{"key":"bibr5-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.029."},{"key":"bibr6-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0793"},{"key":"bibr7-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1186\/ar4051"},{"key":"bibr8-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel314"},{"key":"bibr9-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1002\/art.23303"},{"key":"bibr10-2324709618757260","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/537613."}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709618757260","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2324709618757260","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709618757260","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:59:37Z","timestamp":1777449577000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2324709618757260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,1]]},"references-count":10,"alternative-id":["10.1177\/2324709618757260"],"URL":"https:\/\/doi.org\/10.1177\/2324709618757260","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,1]]},"article-number":"2324709618757260"}}