{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:35:25Z","timestamp":1777671325812,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Multiple myeloma is defined as the neoplastic proliferation of plasma cells resulting in a monoclonal gammopathy. The classic presentation of a patient is someone who presents with bone pain, osteopenia, or new onset fractures. We present a case of multiple myeloma presenting as Evan\u2019s syndrome (ES). Evan\u2019s syndrome is autoimmune hemolytic anaemia with autoimmune thrombocytopenia. A 44-year-old female was referred from her primary physician to the hospital as laboratory testing revealed haemoglobin of 5 gm\/dL. The patient reported a two-month history of fatigue and a sixty-pound weight loss. Laboratory results demonstrated autoimmune hemolytic anaemia, C3 positivity, elevated immunoglobulin (Ig)G, elevated lactate dehydrogenase (LDH), low haptoglobin, elevated reticulocyte count, elevated RDW-CV (red blood cell distribution width-corpuscular volume), positive direct Coombs test, thrombocytopenia, and proteinuria, all of which led to an underlying ES. The patient was started on intravenous steroids followed by oral steroids. A flow cytometry, serum protein electrophoresis, and cytogenetics were obtained. A bone marrow biopsy revealed multiple myeloma and she was started on Bortezomib treatment. We present the fifth reported case of Evan\u2019s syndrome and multiple myeloma.<\/jats:p>","DOI":"10.1177\/2324709619852760","type":"journal-article","created":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T03:08:58Z","timestamp":1560481738000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["A Rare Case of Multiple Myeloma Presenting as Evan\u2019s Syndrome"],"prefix":"10.1177","volume":"7","author":[{"given":"Anthony","family":"Karapetians","sequence":"first","affiliation":[{"name":"UCLA\u2014Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8863-9399","authenticated-orcid":false,"given":"Tushar","family":"Bajaj","sequence":"additional","affiliation":[{"name":"UCLA\u2014Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Valdes","sequence":"additional","affiliation":[{"name":"UCLA\u2014Kern Medical, Bakersfield, CA, USA"},{"name":"Ross University, Miramar, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Heidari","sequence":"additional","affiliation":[{"name":"UCLA\u2014Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,6,14]]},"reference":[{"key":"bibr1-2324709619852760","doi-asserted-by":"publisher","DOI":"10.2147\/JBM.S176144"},{"key":"bibr2-2324709619852760","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjhh.2015.03.002"},{"key":"bibr3-2324709619852760","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2016.25.127.10750"},{"key":"bibr4-2324709619852760","volume":"2016","author":"Al-Ammari M","year":"2016","journal-title":"BMJ Case Rep"},{"key":"bibr5-2324709619852760","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.2922"},{"key":"bibr6-2324709619852760","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2009.01948.x"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709619852760","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2324709619852760","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709619852760","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:00:11Z","timestamp":1777449611000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2324709619852760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":6,"alternative-id":["10.1177\/2324709619852760"],"URL":"https:\/\/doi.org\/10.1177\/2324709619852760","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2324709619852760"}}