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A 65-year-old patient with a past medical history of substance abuse and chronic kidney disease presents to the emergency department with sudden-onset chest pain and shortness of breath. Ventilation-perfusion scan revealed filling defect most notably in the lingual lobe. He was later discharged on warfarin for the management of pulmonary embolism. The patient presented to the emergency department 2 weeks later with similar complaints; the international normalized ratio was subtherapeutic, and urine drug screen was positive for cocaine. Repeat ventilation-perfusion scan revealed no filling defects. Follow-up bilateral venous Doppler of lower extremities and D-dimer were within normal limits.<\/jats:p>","DOI":"10.1177\/2324709620906962","type":"journal-article","created":{"date-parts":[[2020,2,14]],"date-time":"2020-02-14T02:12:51Z","timestamp":1581646371000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Cocaine-Induced Ventilation\/Perfusion Mismatch Mimicking Pulmonary Embolism"],"prefix":"10.1177","volume":"8","author":[{"given":"Phani Keerthi","family":"Surapaneni","sequence":"first","affiliation":[{"name":"Morehouse School of Medicine, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Temidayo","family":"Abe","sequence":"additional","affiliation":[{"name":"Morehouse School of Medicine, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norberto","family":"Fas","sequence":"additional","affiliation":[{"name":"Morehouse School of Medicine, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"key":"bibr1-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax1532"},{"key":"bibr2-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.940569"},{"key":"bibr3-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bky007"},{"key":"bibr4-2324709620906962","doi-asserted-by":"publisher","DOI":"10.15406\/jlprr.2017.04.00121"},{"key":"bibr5-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1080\/10550887.2013.795469"},{"key":"bibr6-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90080-H"},{"key":"bibr7-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.105.13.1529"},{"key":"bibr8-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-8807(01)00074-6"},{"key":"bibr9-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.301436"},{"key":"bibr10-2324709620906962","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0000000000000511"},{"key":"bibr11-2324709620906962","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.894565"},{"key":"bibr12-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2010-0097OC"},{"key":"bibr13-2324709620906962","first-page":"e4700","volume":"11","author":"Sharma T","year":"2019","journal-title":"Cureus"},{"key":"bibr14-2324709620906962","doi-asserted-by":"publisher","DOI":"10.2484\/rcr.v7i3.714"},{"key":"bibr15-2324709620906962","first-page":"326","volume":"40","author":"Hart BL","year":"1989","journal-title":"Can Assoc Radiol J"},{"key":"bibr16-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03440200057023"},{"key":"bibr17-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2010.07.002"},{"key":"bibr18-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2016.01.009"},{"key":"bibr19-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-004-0929-0"},{"key":"bibr20-2324709620906962","first-page":"1062","volume":"22","author":"Mendelson DS","year":"1981","journal-title":"J Nucl Med"},{"key":"bibr21-2324709620906962","doi-asserted-by":"publisher","DOI":"10.4103\/ijnm.IJNM_60_18"},{"key":"bibr22-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199501000-00016"},{"key":"bibr23-2324709620906962","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-200411000-00028"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709620906962","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2324709620906962","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2324709620906962","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:00:23Z","timestamp":1777449623000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2324709620906962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":23,"alternative-id":["10.1177\/2324709620906962"],"URL":"https:\/\/doi.org\/10.1177\/2324709620906962","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"article-number":"2324709620906962"}}