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In this article, we describe 2 unique cases of malignancy, primary prostate carcinoma and serous carcinoma of the ovary, both of which disseminated to sites of prior trauma. We review the available literature, discuss proposed pathophysiology, and highlight the need for further investigations along with increased clinician awareness.<\/jats:p>","DOI":"10.1177\/2324709621997248","type":"journal-article","created":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T06:48:11Z","timestamp":1614235691000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Locus Minoris Resistentiae: Two Cases of Malignant Metastasis and Review of Literature"],"prefix":"10.1177","volume":"9","author":[{"given":"Donya","family":"Farmand","sequence":"first","affiliation":[{"name":"Department of Medicine, Kern Medical-UCLA, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C.","family":"Valdez","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kern Medical-UCLA, Bakersfield, CA, 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