{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T03:01:38Z","timestamp":1781578898884,"version":"3.54.5"},"reference-count":39,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Combined central retinal artery and vein occlusion (CCRAVO) is a rare entity characterized by features of tortuous retinal veins, retinal hemorrhage, optic disk edema and pallor, macula edema, cherry-red spot, and cotton-wool spots. The occurrence of CCRAVO in the adult population is often in the setting of systemic disease; while CCRAVO in the pediatric population is frequently associated with infection of the sinuses, preseptal cellulitis, or orbital cellulitis. It has been hypothesized that CCRAVO can result from methicillin-resistant Staphylococcus aureus (MRSA) sepsis-induced coagulation disturbances, orbital cellulitis, and even orbital compartment syndrome; however, there are insufficient reports of this complication. This case report sheds light on one such case with irreversible vision loss as a sequela.<\/jats:p>","DOI":"10.1177\/23247096231165728","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T02:49:39Z","timestamp":1681872579000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Methicillin-Resistant\n                    <i>Staphylococcus aureus<\/i>\n                    Sepsis and Orbital Cellulitis Leading to a Combined Central Retinal Artery and Vein Occlusion: A Case Report"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2525-7980","authenticated-orcid":false,"given":"Devanshi Narendra","family":"Damani","sequence":"first","affiliation":[{"name":"Texas Tech University Health Sciences Center El Paso, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8143-3331","authenticated-orcid":false,"given":"Dylan Matthew","family":"Salazar","sequence":"additional","affiliation":[{"name":"Texas Tech University Health Sciences Center El Paso, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piya","family":"Kositangool","sequence":"additional","affiliation":[{"name":"Texas Tech University Health Sciences Center El Paso, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Maria","family":"Prospero Ponce","sequence":"additional","affiliation":[{"name":"Texas Tech University Health Sciences Center El Paso, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Dihowm","sequence":"additional","affiliation":[{"name":"Texas Tech University Health Sciences Center El Paso, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"bibr1-23247096231165728","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S328931"},{"key":"bibr2-23247096231165728","first-page":"7202731","volume":"2019","author":"Wang H","year":"2019","journal-title":"J Ophthalmol"},{"key":"bibr3-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/40.10.1195"},{"key":"bibr4-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.164"},{"key":"bibr5-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1177\/0961203309345751"},{"key":"bibr6-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0b013e31822476d7"},{"key":"bibr7-23247096231165728","volume":"2017","author":"Parchand SM","year":"2017","journal-title":"BMJ Case Rep"},{"key":"bibr8-23247096231165728","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_996_18"},{"key":"bibr9-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajoc.2020.100833"},{"key":"bibr10-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700685"},{"key":"bibr11-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-248425"},{"key":"bibr12-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701355"},{"key":"bibr13-23247096231165728","volume":"2016","author":"Parchand SM.","year":"2016","journal-title":"Case Rep"},{"key":"bibr14-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1159\/000513794"},{"key":"bibr15-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2006.00693.x"},{"key":"bibr16-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1159\/000442788"},{"key":"bibr17-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-022-02278-1"},{"key":"bibr18-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2015.03.033"},{"key":"bibr19-23247096231165728","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S217742"},{"key":"bibr20-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0000000000000027"},{"key":"bibr21-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0b013e31828eef20"},{"key":"bibr22-23247096231165728","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.27077"},{"key":"bibr23-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2021.08.019"},{"key":"bibr24-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700250"},{"issue":"1","key":"bibr25-23247096231165728","first-page":"75","volume":"11","author":"Komolafe OO","year":"2008","journal-title":"Niger J Clin Pract"},{"issue":"3","key":"bibr26-23247096231165728","volume":"43","author":"Matsanga OR","year":"2020","journal-title":"J Fr Ophtalmol"},{"key":"bibr27-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.71.11.834"},{"key":"bibr28-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcab287"},{"key":"bibr29-23247096231165728","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2016.48.4.267"},{"key":"bibr30-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1556730"},{"key":"bibr31-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2015.213"},{"key":"bibr32-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(86)90614-5"},{"key":"bibr33-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.04.005"},{"key":"bibr34-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2232010423"},{"key":"bibr35-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1186\/2047-783X-18-27"},{"key":"bibr36-23247096231165728","doi-asserted-by":"publisher","DOI":"10.28920\/dhm50.4.431-436"},{"key":"bibr37-23247096231165728","doi-asserted-by":"publisher","DOI":"10.1177\/1120672120909181"},{"key":"bibr38-23247096231165728","doi-asserted-by":"publisher","DOI":"10.4103\/1319-4534.310406"},{"key":"bibr39-23247096231165728","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S189082"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23247096231165728","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/23247096231165728","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23247096231165728","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:03:17Z","timestamp":1777449797000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/23247096231165728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":39,"alternative-id":["10.1177\/23247096231165728"],"URL":"https:\/\/doi.org\/10.1177\/23247096231165728","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"23247096231165728"}}