{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:48:30Z","timestamp":1777672110972,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Histoplasma capsulatum is a dimorphic fungus found in certain parts of North, Central, and South America. Transmission is primarily through airborne inoculation from inhaled fungal microconidia. Histoplasmosis is typically a self-limited mycosis; however, in patients with immunodeficiency, disseminated disease can occur and may lead to high disease burden. This report studies a case of disseminated histoplasmosis in a patient newly diagnosed with human immunodeficiency virus. His presentation on admission was consistent with infectious pulmonary granulomatous disease, and further imaging and laboratory results showed evidence of multi-organ involvement. It is likely his presentation in Central California was a reactivation infection after inoculation in Central America many years ago.<\/jats:p>","DOI":"10.1177\/23247096231205347","type":"journal-article","created":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T08:30:26Z","timestamp":1696840226000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Disseminated Histoplasmosis in Central California Seen in an Immunocompromised Patient"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8149-5768","authenticated-orcid":false,"given":"Kishan","family":"Ghadiya","sequence":"first","affiliation":[{"name":"UCLA-Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Dunn","sequence":"additional","affiliation":[{"name":"UCLA-Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurpal","family":"Singh","sequence":"additional","affiliation":[{"name":"UCLA-Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8246-3871","authenticated-orcid":false,"given":"Hobart","family":"Lai","sequence":"additional","affiliation":[{"name":"UCLA-Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Garcia-Pacheco","sequence":"additional","affiliation":[{"name":"UCLA-Kern Medical, Bakersfield, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,9]]},"reference":[{"key":"bibr1-23247096231205347","volume-title":"Histoplasmosis","author":"Akram SM","year":"2023"},{"key":"bibr2-23247096231205347","doi-asserted-by":"publisher","DOI":"10.3201\/eid2403.171258"},{"key":"bibr3-23247096231205347","doi-asserted-by":"publisher","DOI":"10.2147\/HIV.S185631"},{"key":"bibr4-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/807537"},{"key":"bibr5-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1378\/chest.29.6.649"},{"key":"bibr6-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30354-2"},{"key":"bibr7-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-016-0538-7"},{"key":"bibr8-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1053\/srin.2001.24244"},{"key":"bibr9-23247096231205347","volume-title":"Itraconazole","author":"Kurn H","year":"2023"},{"key":"bibr10-23247096231205347","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S34434."},{"key":"bibr11-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199011000-00004"},{"key":"bibr12-23247096231205347","doi-asserted-by":"publisher","DOI":"10.1086\/513653"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23247096231205347","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/23247096231205347","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23247096231205347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:03:44Z","timestamp":1777449824000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/23247096231205347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":12,"alternative-id":["10.1177\/23247096231205347"],"URL":"https:\/\/doi.org\/10.1177\/23247096231205347","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"23247096231205347"}}