{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:49:34Z","timestamp":1777672174047,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease. The patient completed 28 sessions of radiation therapy, resulting in an improvement in his throat pain and hoarseness. Given the patient\u2019s age and lack of traditional risk factors for head and neck cancers, his hoarseness and odynophagia proved to be a diagnostic conundrum. Although infrequent, soft tissue plasmacytomas should be considered in the differential diagnosis of head and neck tumors.<\/jats:p>","DOI":"10.1177\/23247096241242237","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T04:23:56Z","timestamp":1712291036000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2772-6085","authenticated-orcid":false,"given":"Lefika","family":"Bathobakae","sequence":"first","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shayee","family":"Hasan","sequence":"additional","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aneeqa","family":"Shahid","sequence":"additional","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"St. George\u2019s University School of Medicine, Grenada, West Indies"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shajla","family":"Ajas","sequence":"additional","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehandar","family":"Kumar","sequence":"additional","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohail","family":"Qayyum","sequence":"additional","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amer","family":"Akmal","sequence":"additional","affiliation":[{"name":"St. Joseph\u2019s University Medical Center, Paterson, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,5]]},"reference":[{"key":"bibr1-23247096241242237","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4816"},{"key":"bibr2-23247096241242237","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2013.1712"},{"key":"bibr3-23247096241242237","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S190362"},{"key":"bibr4-23247096241242237","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11154390"},{"key":"bibr5-23247096241242237","unstructured":"Xing Y, Qiu J, Zhou M-L, et al. Prognostic factors of laryngeal solitary extramedullary plasmacytoma: a case report and review of literature. Int J Clin Exp Pathol. 2015;8:2415-2435. 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Extramedullary plasmacytomas of the larynx and para pharyngeal space: imaging and pathologic features. Ear Nose Throat J. 2007;86(9):567-569. 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