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Physical examination and laboratory analysis revealed signs of respiratory distress and thrombocytopenia. The trajectory of his illness led to acute respiratory distress syndrome (ARDS) and hemodynamic instability. Serum testing was positive for hantavirus IgM and IgG antibodies. The patient was managed with supportive care and improved. This case highlights the importance of considering hantavirus when managing patients who develop thrombocytopenia, ARDS, and hemodynamic instability in the appropriate clinical setting.<\/jats:p>","DOI":"10.1177\/23247096241274572","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T14:26:06Z","timestamp":1724336766000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hantavirus Cardiopulmonary syndrome: Another Reason to Avoid Mice"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9377-0980","authenticated-orcid":false,"given":"Mark","family":"Kennedy","sequence":"first","affiliation":[{"name":"Community Hospital, Grand Junction, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Mctabi","sequence":"additional","affiliation":[{"name":"Community Hospital, Grand Junction, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Rickman","sequence":"additional","affiliation":[{"name":"Community Hospital, Grand Junction, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"bibr1-23247096241274572","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12291"},{"key":"bibr2-23247096241274572","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00062-09"},{"key":"bibr3-23247096241274572","unstructured":"Akram SM, Mangat R, Huang B. Hantavirus cardiopulmonary syndrome. StatPearls. Published 2023, Accessed 20 March 2024. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK459378\/"},{"key":"bibr4-23247096241274572","unstructured":"Centers for Disease Control and Prevention. Reported cases of hantavirus disease. Published 2023, Accessed 1 March 2024. https:\/\/www.cdc.gov\/hantavirus\/surveillance\/index.html"},{"key":"bibr5-23247096241274572","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25054"},{"key":"bibr6-23247096241274572","unstructured":"Centers for Disease Control Prevention. Hantavirus Pulmonary Syndrome \u2014- United States: Updated Recommendations for Risk Reduction. 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