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It is characterized histopathologically by tubular atrophy and dilation, interstitial fibrosis, lymphocyte and macrophage-predominant cellular infiltration, and linear deposition of IgG and complement along the tubular basement membrane. We herein present a case of a 69-year-old male who was recently diagnosed with chronic lymphocytic leukemia (CLL) and was referred for evaluation of kidney failure, ultimately diagnosed as anti-TBM antibody nephritis progressing into end-stage kidney disease (ESKD). This case report highlights the management challenges of anti-TBM antibody nephritis as a rare kidney disorder.<\/jats:p>","DOI":"10.1177\/23247096241281612","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T13:21:58Z","timestamp":1727184118000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Anti-Tubular Basement Membrane Antibody Nephritis Manifesting in a Patient With Chronic Lymphocytic Leukemia: A Very Rare Case Report"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2585-7820","authenticated-orcid":false,"given":"Niloufar","family":"Ebrahimi","sequence":"first","affiliation":[{"name":"Loma Linda University Health, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behzad","family":"Najafian","sequence":"additional","affiliation":[{"name":"University of Washington, Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Chen Wongworawat","sequence":"additional","affiliation":[{"name":"Loma Linda University Health, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayna","family":"Norouzi","sequence":"additional","affiliation":[{"name":"Loma Linda University Health, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Abdipour","sequence":"additional","affiliation":[{"name":"Loma Linda University Health, Loma Linda, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,9,24]]},"reference":[{"key":"bibr1-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/6681756"},{"key":"bibr2-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.05.001"},{"key":"bibr3-23247096241281612","volume-title":"Diagnostic Atlas of Renal Pathology","author":"Fogo AB","year":"2017","edition":"3"},{"key":"bibr4-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.20.11323"},{"key":"bibr5-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2000.2103"},{"key":"bibr6-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)42077-1"},{"key":"bibr7-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.375"},{"key":"bibr8-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.132.6.1161"},{"key":"bibr9-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197504242921701"},{"key":"bibr10-23247096241281612","doi-asserted-by":"publisher","DOI":"10.1056\/nejm197408222910803"},{"key":"bibr11-23247096241281612","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-1-21"}],"container-title":["Journal of Investigative Medicine High Impact Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23247096241281612","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/23247096241281612","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23247096241281612","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:04:11Z","timestamp":1777449851000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/23247096241281612"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":11,"alternative-id":["10.1177\/23247096241281612"],"URL":"https:\/\/doi.org\/10.1177\/23247096241281612","relation":{},"ISSN":["2324-7096","2324-7096"],"issn-type":[{"value":"2324-7096","type":"print"},{"value":"2324-7096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"23247096241281612"}}