{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:50:38Z","timestamp":1777672238333,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Investigative Medicine High Impact Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Ewing\u2019s sarcoma, a rare primary bone malignancy primarily affecting adolescents and young adults, typically manifests in the pelvic bones and femur. Primary Ewing\u2019s sarcoma of the sternum is exceptionally rare, constituting less than 1% of cases. We present a case of a 34-year-old man with a 2-month history of anterior chest wall pain initially attributed to muscular spasm. Subsequently, the patient developed a palpable mass and imaging demonstrated a mid-lower sternal lesion with cortical destruction and soft tissue involvement, confirmed as Ewing\u2019s sarcoma on biopsy. In addition, a suspicious lesion was identified in the left distal tibia, which was histologically confirmed as a metastasis from the primary sternal sarcoma. Neoadjuvant chemotherapy preceded partial sternotomy with rib resection and reconstruction, achieving clear surgical margins. Postoperative evaluation showed shrinkage in the sternal lesion and near-resolution of the tibial metastasis. Subsequent chemotherapy cycles resulted in no evidence of the disease on the follow-up positron emission tomography scan. This case underscores the diagnostic challenges of primary sternal Ewing\u2019s sarcoma and emphasizes the importance of early recognition and comprehensive evaluation in managing such rare presentations.<\/jats:p>","DOI":"10.1177\/23247096241286358","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T06:05:12Z","timestamp":1728281112000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Primary Ewing\u2019s Sarcoma of the Sternum in an Adult Male: A Rare Case Report"],"prefix":"10.1177","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5814-9345","authenticated-orcid":false,"given":"Salem K.","family":"Qupp","sequence":"first","affiliation":[{"name":"Al-Quds University, Jerusalem, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iyad M.","family":"Halayqa","sequence":"additional","affiliation":[{"name":"Al-Quds University, Jerusalem, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman J.","family":"Shawahna","sequence":"additional","affiliation":[{"name":"An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amjad","family":"Bdair","sequence":"additional","affiliation":[{"name":"An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seham","family":"Madaka","sequence":"additional","affiliation":[{"name":"Al-Quds University, Jerusalem, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majd","family":"Issa","sequence":"additional","affiliation":[{"name":"Tula State University, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ola","family":"Jawabreh","sequence":"additional","affiliation":[{"name":"An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asala 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