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Azacitidine has been implicated to cause nonhepatic ischemic injury. Here we report a case of severe, short latency drug-induced liver injury following the infusion of azacitidine and venetoclax in a patient which was subsequently mitigated through pretreatment with a vasodilatory agent.<\/jats:p>","DOI":"10.1177\/23247096251344720","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T05:15:24Z","timestamp":1747804524000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Rapid Onset Liver Injury Due to Azacitidine Through Possibly a Unique Mechanism of Hypoperfusion of the Liver"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2083-1293","authenticated-orcid":false,"given":"Dilara","family":"Hatipoglu","sequence":"first","affiliation":[{"name":"University of Pennsylvania, Philadelphia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arsia","family":"Jamali","sequence":"additional","affiliation":[{"name":"University of Pennsylvania, Philadelphia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Sheng","sequence":"additional","affiliation":[{"name":"University of Pennsylvania, Philadelphia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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