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Here, we describe a case of a 66-year-old male who was admitted with the presumed diagnosis of rhabdomyolysis in the setting of chronic statin use but was later confirmed to have statin-induced IMNM after his symptoms were refractory to treatment. This case highlights the importance of having a high clinical suspicion for statin-induced IMNM when statin-associated muscle symptoms fail to resolve after the discontinuation of statins.<\/jats:p>","DOI":"10.1177\/23247096251344727","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T03:11:09Z","timestamp":1748229069000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0044-8082","authenticated-orcid":false,"given":"Leo","family":"Sakai","sequence":"first","affiliation":[{"name":"Loma Linda University Health, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Kazbour","sequence":"additional","affiliation":[{"name":"Loma Linda University Health, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Huang","sequence":"additional","affiliation":[{"name":"Jerry L. Pettis Memorial Veteran\u2019s Hospital, Loma Linda, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2022.09.001"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.14740\/jmc4039"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1515161"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30254-0"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-018-0732-6"},{"issue":"5","key":"e_1_3_2_7_2","article-title":"Statin-induced immune-mediated necrotizing myopathy: an increasingly recognized inflammatory myopathy","volume":"12","author":"Stroie OP","year":"2020","unstructured":"Stroie OP, Boster J, Surry L. Statin-induced immune-mediated necrotizing myopathy: an increasingly recognized inflammatory myopathy. 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