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We found a sized-up gallbladder polyp and a liver tumor. She underwent laparoscopic segment 8 subsegmentectomy and cholecystectomy for suspected malignancy. Pathology revealed aggressive follicular lymphoma of the liver and gallbladder. Immunohistochemical staining was positive for CD10, CD20, CD23, CD79a, BCL-2, and BCL-6, and negative for CD3, CD5, and cyclin-D1. Primary hepatic lymphoma and gallbladder polyp are accidental, and diagnosis is difficult without tissue biopsy or specimens. Laparoscopic hepatectomy facilitates accurate diagnosis and early postoperative recovery, enabling rapid chemotherapy administration.<\/jats:p>","DOI":"10.1177\/23247096251348909","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T03:07:16Z","timestamp":1750388836000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Primary Non-Hodgkin Lymphoma of the Liver and Gallbladder Diagnosed by Laparoscopic Segment 8 Subsegmentectomy and Cholecystectomy: A Rare Case Report"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6813-9584","authenticated-orcid":false,"given":"Toshikatsu","family":"Nitta","sequence":"first","affiliation":[{"name":"Division of Surgery Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6596-2599","authenticated-orcid":false,"given":"Masatsugu","family":"Ishii","sequence":"additional","affiliation":[{"name":"Division of Surgery Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8800-9541","authenticated-orcid":false,"given":"Masataka","family":"Taki","sequence":"additional","affiliation":[{"name":"Division of Surgery Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryutaro","family":"Kubo","sequence":"additional","affiliation":[{"name":"Division of Surgery Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akitada","family":"Sada","sequence":"additional","affiliation":[{"name":"Division of Surgery Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Takeshita","sequence":"additional","affiliation":[{"name":"Department of Pathology, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Ishibashi","sequence":"additional","affiliation":[{"name":"Division of Surgery Gastroenterological Center, Medico Shunju Shiroyama Hospital, Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2004.10.010"},{"issue":"10","key":"e_1_3_3_3_2","first-page":"12955","article-title":"Clinicopathological feature of primary hepatic diffuse large B-cell lymphoma: a report of seven cases and a literature review","volume":"8","author":"Zheng J","year":"2015","unstructured":"Zheng J, Hou Y, Zhou R, et al. 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