{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:07:30Z","timestamp":1790262450904,"version":"4.1.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["LGBT Health"],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>This study evaluated reproductive intentions, fertility-related knowledge, prior fertility counseling, and factors associated with reproductive intentions among transgender and nonbinary individuals receiving care at a Brazilian public reference center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional study with a qualitative component was conducted between July and November 2025 in a specialized gender-affirming care clinic in Brazil. Quantitative data included sociodemographic characteristics, reproductive history, gender-affirming hormone therapy (GAHT), and fertility-related variables. Logistic regression was used to assess factors associated with desire for future parenthood. Responses to a single open-ended question regarding perceived effects of GAHT on fertility were analyzed using thematic content analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Eighty-two participants were included (mean age 27.5 \u00b1 7.4 years). Most identified as transgender men (65.9%), followed by transgender women (26.8%) and nonbinary individuals (7.3%); 79.3% were receiving GAHT. Although 63.4% expressed a desire for future parenthood, only 7.3% had children. Current interest in fertility preservation was reported by 20.8% (15\/72). Having children (adjusted odds ratio [aOR] = 0.03; 95% confidence interval [CI]: 0.001\u20130.62;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.023) and each additional year of GAHT duration (aOR = 0.83; 95% CI: 0.70\u20130.99;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.038) were associated with lower odds of desiring future parenthood. Sex assigned at birth was not independently associated with reproductive intentions. Qualitative analysis revealed misconceptions, uncertainty, and conditional beliefs regarding fertility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Desire for future parenthood was common among transgender and nonbinary individuals, whereas engagement with fertility preservation remained limited. These findings highlight the need for longitudinal, patient-centered reproductive counseling integrated into gender-affirming care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23258292261480721","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:12:45Z","timestamp":1788257565000},"page":"430-437","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Reproductive Intentions and Fertility Preservation Among Transgender and Nonbinary Individuals: A Cross-Sectional Study in Brazil"],"prefix":"10.1177","volume":"13","author":[{"given":"Let\u00edcia A.","family":"Mendon\u00e7a","sequence":"first","affiliation":[{"name":"Reference Center for Comprehensive Trans-specific Health Care (CRAIST), University Hospital, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela G.","family":"Silva","sequence":"additional","affiliation":[{"name":"Reference Center for Comprehensive Trans-specific Health Care (CRAIST), University Hospital, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris T.T.","family":"Umeda","sequence":"additional","affiliation":[{"name":"School of Medicine, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phelipe E.","family":"Silva","sequence":"additional","affiliation":[{"name":"Reference Center for Comprehensive Trans-specific Health Care (CRAIST), University Hospital, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."},{"name":"School of Dentistry, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5268-0595","authenticated-orcid":false,"given":"Heitor Bernardes P.","family":"Delfino","sequence":"additional","affiliation":[{"name":"Reference Center for Comprehensive Trans-specific Health Care (CRAIST), University Hospital, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."},{"name":"Department of Public Health, School of Medicine, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Toffoli-Ribeiro","sequence":"additional","affiliation":[{"name":"Reference Center for Comprehensive Trans-specific Health Care (CRAIST), University Hospital, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil."},{"name":"Department of Gynecology and Obstetrics, School of Medicine, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, 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