{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:10:57Z","timestamp":1777853457033,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2013,9,3]],"date-time":"2013-09-03T00:00:00Z","timestamp":1378166400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>\n                    Cryptococcal meningitis (CM) remains a significant HIV-associated opportunistic infection in Southeast Asia and Africa, with a high burden of disease and a high mortality rate despite the availability of antiretroviral therapy (ART). We retrospectively examined the utility of cryptococcal antigen screening to identify risk for CM among 211 Thai women initiating ART. Antigenemia prevalence was 11% (n = 9) among 84 women with a CD4 count &lt;100 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . Screening identified all women who later developed CM. Cryptococcal antigen titers decreased over time with ART. Our study confirmed findings from previous studies in Thailand and South Africa and provided novel observational data regarding the course of cryptococcal antigenemia in patients initiating ART and the poor efficacy of low-dose fluconazole prophylaxis in preventing CM among patients with antigenemia.\n                  <\/jats:p>","DOI":"10.1177\/2325957413500533","type":"journal-article","created":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:47:23Z","timestamp":1378255643000},"page":"434-437","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Utility of Cryptococcal Antigen Screening and Evolution of Asymptomatic Cryptococcal Antigenemia among HIV-Infected Women Starting Antiretroviral Therapy in Thailand"],"prefix":"10.1177","volume":"13","author":[{"given":"Candice K.","family":"Kwan","sequence":"first","affiliation":[{"name":"Division of HIV\/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA"},{"name":"Epidemic Intelligence Service, CDC, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanna","family":"Leelawiwat","sequence":"additional","affiliation":[{"name":"Thailand Ministry of Public Health-US CDC Collaboration, Nonthaburi, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Poj","family":"Intalapaporn","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, Rajavithi Hospital, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thanomsak","family":"Anekthananon","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boonyos","family":"Raengsakulrach","sequence":"additional","affiliation":[{"name":"Thailand Ministry of Public Health-US CDC Collaboration, Nonthaburi, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip J.","family":"Peters","sequence":"additional","affiliation":[{"name":"Division of HIV\/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet M.","family":"McNicholl","sequence":"additional","affiliation":[{"name":"Division of HIV\/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin J.","family":"Park","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, CDC, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle S.","family":"McConnell","sequence":"additional","affiliation":[{"name":"Thailand Ministry of Public Health-US CDC Collaboration, Nonthaburi, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Weidle","sequence":"additional","affiliation":[{"name":"Division of HIV\/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,9,3]]},"reference":[{"key":"bibr1-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328322ffac"},{"key":"bibr2-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32832be0fc"},{"key":"bibr3-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1086\/587667"},{"key":"bibr4-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2010.010235"},{"key":"bibr5-2325957413500533","volume-title":"Rapid Advice: Diagnosis, Prevention, and Management of Cryptococcal Disease in HIV-Infected Adults, Adolescents, and Children","author":"WHO","year":"2011"},{"key":"bibr6-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70170-5"},{"key":"bibr7-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000233"},{"key":"bibr8-2325957413500533","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2004.00201.x"},{"key":"bibr9-2325957413500533","volume-title":"Thailand National Antiretroviral Treatment Guideline 2006\/2007","author":"Department of Disease Control, M. o. 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