{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:04:32Z","timestamp":1791198272430,"version":"4.1.0"},"reference-count":42,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T00:00:00Z","timestamp":1403049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>In resource-limited settings, malnutrition is the major cause of death in young children, but the precise benefits of nutritional supplementation for HIV-infected children are not well understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two researchers reviewed studies conducted in low- or middle-income countries that involved macro- and micronutrient supplementation in HIV-infected individuals \u226418 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifteen studies focused on micronutrients, including vitamin A, zinc, multivitamins, and multiple-micronutrient supplementation. The 8 macronutrient studies focused on ready-to-use foods (4 studies), spirulina, whey protein, general food rations, and F75 and F100 starter formulas. Vitamin A was associated with improved mortality rates, ranging from 28% to 63%. Multiple-micronutrient supplementations were not associated with improvement of measured health outcomes. Ready-to-use foods were associated with improvement in certain anthropometrics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Periodic vitamin A supplementation is associated with reduced mortality. Macronutrient supplementation is linked to improved anthropometrics. More research is needed to determine how nutritional supplementation benefits this particularly vulnerable population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/2325957414539044","type":"journal-article","created":{"date-parts":[[2014,6,18]],"date-time":"2014-06-18T22:04:53Z","timestamp":1403129093000},"page":"313-323","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["A Systematic Review of Nutritional Supplementation in HIV-Infected Children in Resource-Limited Settings"],"prefix":"10.1177","volume":"14","author":[{"given":"Megan S.","family":"McHenry","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Health Services Research, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avika","family":"Dixit","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Health Services Research, Indiana University School of Medicine, Indianapolis, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel C.","family":"Vreeman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Health Services Research, Indiana University School of Medicine, Indianapolis, IN, USA"},{"name":"USAID-Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,6,18]]},"reference":[{"key":"bibr1-2325957414539044","volume-title":"The Effects of Nutritional Interventions in HIV\/AIDS:Micronutrients","author":"Irlam J HG","year":"2007"},{"key":"bibr2-2325957414539044","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1992.tb12371.x"},{"key":"bibr3-2325957414539044","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(21)03142-4"},{"issue":"2","key":"bibr4-2325957414539044","first-page":"121","volume":"11","author":"Henderson RA","year":"1995","journal-title":"Nutrition"},{"key":"bibr5-2325957414539044","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.112.034637"},{"key":"bibr6-2325957414539044","first-page":"CD006736","volume":"1","author":"Adetifa I","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr7-2325957414539044","first-page":"CD003650","volume":"12","author":"Irlam JH","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr8-2325957414539044","unstructured":"Countries and Economies. 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