{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:11:30Z","timestamp":1777853490175,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,8,22]],"date-time":"2014-08-22T00:00:00Z","timestamp":1408665600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p>\n                    Interferon gamma release assays (IGRAs) are poorly studied in HIV-infected children. The authors prospectively evaluated QuantiFERON-TB Gold results and family-described tuberculosis (TB) risk factors in 100 HIV-infected children in Botswana. Median age was 10.2 years; 58 were girls, 92 had received the Bacillus Calmette\u2013Gu\u00e9rin (BCG) vaccine, 98 were receiving antiretroviral therapy, and the median body mass index was 15.8 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    . Eighty-nine children had undetectable viral loads and the median CD4 count was 962 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . Eighteen children had been treated for TB in the last 3 years. In the last 3 years, 36 (including 9 with TB) had contact with persons with TB (26 within\/15 outside the home and 5 had &gt;1 contact). In all, 96 children had negative IGRAs, 3 were indeterminate, and 1 was positive. The positive IGRA was reported in a child treated for TB prior to 3 years. Interferon \u03b3 release assay positivity was rare in this pediatric cohort living in an area with a high prevalence of TB.\n                  <\/jats:p>","DOI":"10.1177\/2325957414547432","type":"journal-article","created":{"date-parts":[[2014,8,22]],"date-time":"2014-08-22T22:36:01Z","timestamp":1408746961000},"page":"4-7","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Performance of the QuantiFERON-TB Gold Interferon Gamma Release Assay among HIV-Infected Children in Botswana"],"prefix":"10.1177","volume":"14","author":[{"given":"Andrea T.","family":"Cruz","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA"},{"name":"Tuberculosis Initiative, Texas Children\u2019s Hospital, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marape","family":"Marape","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA"},{"name":"Tuberculosis Initiative, Texas Children\u2019s Hospital, Houston, TX, USA"},{"name":"Botswana-Baylor Children\u2019s Clinical Centre of Excellence, Gaborone, Botswana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward A.","family":"Graviss","sequence":"additional","affiliation":[{"name":"Department of Pathology and Genomic Medicine, The Methodist Hospital Research Institute, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey R.","family":"Starke","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA"},{"name":"Tuberculosis Initiative, Texas Children\u2019s Hospital, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,8,22]]},"reference":[{"key":"bibr1-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047542"},{"key":"bibr2-2325957414547432","unstructured":"World Health Organization. Global tuberculosis report: 2012. http:\/\/apps.who.int\/iris\/bitstream\/10665\/75938\/1\/9789241564502_eng.pdf. Accessed December 13, 2013."},{"key":"bibr3-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-200933"},{"key":"bibr4-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31827d77b7"},{"key":"bibr5-2325957414547432","unstructured":"World Health Organization. Use of tuberculosis interferon gamma release assays (IGRAs) in low- and middle-income countries: policy statement; 2011. http:\/\/whqlibdoc.who.int\/publications\/2011\/9789241502672_eng.pdf. Accessed December 13, 2013."},{"key":"bibr6-2325957414547432","unstructured":"World Health Organization Botswana tuberculosis profile; 2013. https:\/\/extranet.who.int\/sree\/Reports?op=Replet&name=%2FWHO_HQ_Reports%2FG2%2FPROD%2FEXT%2FTBCountryProfile&ISO2=BW&LAN=EN&outtype=html. Accessed December 5, 2013."},{"key":"bibr7-2325957414547432","unstructured":"QuantiFERON\u00ae-TB Gold [package insert]. Germantown, MD: Qiagen; 2006. http:\/\/www.cellestis.com\/IRM\/Company\/ShowPage.aspx?CPID=1171. Accessed December 16, 2013."},{"key":"bibr8-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181a16394"},{"key":"bibr9-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-012-0265-2"},{"key":"bibr10-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-220"},{"key":"bibr11-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-3299"},{"key":"bibr12-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-138"},{"key":"bibr13-2325957414547432","first-page":"301056","volume":"2012","author":"Pokam BT","year":"2012","journal-title":"Tuberc Res Treat"},{"key":"bibr14-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-88"},{"key":"bibr15-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004220"},{"key":"bibr16-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200604-465OC"},{"key":"bibr17-2325957414547432","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00096707"}],"container-title":["Journal of the International Association of Providers of AIDS Care (JIAPAC)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2325957414547432","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2325957414547432","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2325957414547432","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:53:16Z","timestamp":1777503196000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2325957414547432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,22]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1177\/2325957414547432"],"URL":"https:\/\/doi.org\/10.1177\/2325957414547432","relation":{},"ISSN":["2325-9582","2325-9582"],"issn-type":[{"value":"2325-9582","type":"print"},{"value":"2325-9582","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,22]]}}}