{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T21:55:00Z","timestamp":1779400500299,"version":"3.53.1"},"reference-count":11,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T00:00:00Z","timestamp":1440028800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:p>\n                    The authors sought to assess whether viral load (VL) monitoring frequency was associated with differential rates of virologic failure (VF) among HIV Outpatient Study (HOPS) participants seen during 1999 to 2013, who had maintained VL &lt;50 copies\/mL, CD4 counts \u2265300 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    , and been prescribed a stable combination antiretroviral regimen for at least 2 years. The authors required VL and CD4 testing to have occurred regularly for the entire 2-year period. The authors assessed rates of VF comparing patients who maintained a frequent VL testing (\u22653 VLs) to those who shifted to a less frequent schedule (2 VL) after the 2-year period. Virologic failure was observed among 116 of 573 participants. The authors did not detect statistically significant difference in frequency of VF among patients undergoing frequent (21.0%) versus less frequent VL testing (19.6%), even after multivariable adjustment. Biannual VL monitoring for stable patients with aviremia could generate substantial cost savings without the increased risk of VF.\n                  <\/jats:p>","DOI":"10.1177\/2325957415600799","type":"journal-article","created":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T22:24:19Z","timestamp":1440109459000},"page":"536-543","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["HIV Viral Load Monitoring Frequency and Risk of Treatment Failure among Immunologically Stable HIV-Infected Patients Prescribed Combination Antiretroviral Therapy"],"prefix":"10.1177","volume":"14","author":[{"given":"Benjamin","family":"Young","sequence":"first","affiliation":[{"name":"APEX Family Medicine, Denver, CO, USA"},{"name":"International Association of Providers of AIDS Care, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel L. D.","family":"Hart","sequence":"additional","affiliation":[{"name":"Cerner Corporation, Kansas City, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Buchacz","sequence":"additional","affiliation":[{"name":"Division of HIV\/AIDS Prevention, Center for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mia","family":"Scott","sequence":"additional","affiliation":[{"name":"APEX Family Medicine, Denver, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Palella","sequence":"additional","affiliation":[{"name":"Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Division of HIV\/AIDS Prevention, Center for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,8,20]]},"reference":[{"key":"bibr1-2325957415600799","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081355"},{"key":"bibr2-2325957415600799","doi-asserted-by":"publisher","DOI":"10.1086\/644768"},{"key":"bibr3-2325957415600799","unstructured":"Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. Web site. http:\/\/aidsinfo.nih.gov\/ContentFiles\/AdultandAdolescentGL.pdf. Section Accessed August 4, 2015."},{"key":"bibr4-2325957415600799","volume-title":"Consolidated Guidelines on General HIV Care and the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach","author":"World Health Organization","year":"2013"},{"key":"bibr5-2325957415600799","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328304b38b"},{"key":"bibr6-2325957415600799","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32833a3967"},{"key":"bibr7-2325957415600799","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015051"},{"key":"bibr8-2325957415600799","volume-title":"2nd ID Week Conference (IDWeek 2013)","author":"Sanasi K","year":"2013"},{"key":"bibr9-2325957415600799","unstructured":"Centers for Medicare and Medicaid Services. Clinical diagnostic laboratory fee schedule. Web site. https:\/\/www.cms.gov\/Medicare\/Medicare-Fee-for-Service-Payment\/ClinicalLabFeeSched\/clinlab.html. 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