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They are multiple and change over time. Considering temporality in patients\u2019 perceptions of adherence barriers could improve adherence management. We explored how temporality manifests itself in patients\u2019 perceptions of adherence barriers. We conducted 2 semi-structured focus groups on adherence barriers with 12 adults with HIV which were analyzed with grounded theory. A third focus group served to validate the results obtained. Three temporal categories were manifest in HIV-positive patients\u2019 perceptions of barriers: (1) imprinting (events with lasting impacts on patients), (2) domino effects (chain of life events), and (3) future shadowing (apprehension about long-term adherence). An overarching theme, weathering (gradual erosion of abilities to adhere), traversed these categories. These temporalities explain how similar barriers may be perceived differently by patients. They could be useful to providers for adapting their interventions and improving understanding of patients\u2019 subjective experience of adherence.<\/jats:p>","DOI":"10.1177\/2325958218759208","type":"journal-article","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T05:08:39Z","timestamp":1519362519000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["HIV-Positive Patients\u2019 Perceptions of Antiretroviral Therapy Adherence in Relation to Subjective Time: Imprinting, Domino Effects, and Future Shadowing"],"prefix":"10.1177","volume":"17","author":[{"given":"David","family":"Lessard","sequence":"first","affiliation":[{"name":"Department of Family Medicine, McGill University, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Toupin","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, McGill University, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Engler","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, McGill University, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e0s","family":"L\u00e8n\u00e0rt","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, McGill University, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"I-Score Consulting Team","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Lebouch\u00e9","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, McGill University, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,2,23]]},"reference":[{"key":"bibr1-2325958218759208","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-9566.2008.01120.x"},{"key":"bibr2-2325958218759208","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2015.47.4.231"},{"key":"bibr3-2325958218759208","unstructured":"World Health Organization. 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