{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:16:19Z","timestamp":1788383779259,"version":"build-2803163510"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:p>Despite decreasing incidence of toxoplasmosis encephalitis(TE) among people living with HIV(PLWH) in the late antiretroviral era, U.S. safety-net hospitals still see significant numbers of admissions for TE. Little is known about this population, their healthcare utilization and long-term outcomes. We conducted an 8-year retrospective review of PLWH with TE at a safety-net hospital. Demographics, clinical characteristics, treatments, readmissions, and outcomes were collected. We used chi-squared test to evaluate 6-month all-cause readmission and demographic\/clinical characteristics. Of 38 patients identified, 79% and 40% had a new diagnosis of TE and HIV respectively. 59% had 6-month all-cause readmission. Social factors were associated with readmission (uninsured (p = 0.036), Spanish as primary language (p = 0.017), non-adherence (p = 0.030)) and not markers of clinical severity (ICU admission, steroid-use, concomitant infections, therapeutic adverse events). Despite high readmission rates, at follow-up, 60% had a complete response, 30% had a partial response. Improving TE outcomes requires focus on culturally competent, coordinated care.<\/jats:p>","DOI":"10.1177\/23259582211043863","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T05:51:10Z","timestamp":1634622670000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Toxoplasmosis Encephalitis: A Cross-Sectional Analysis at a U.S. Safety-Net Hospital in the Late cART Era"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7146-9162","authenticated-orcid":false,"given":"Abby","family":"Lau","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamta Khandelwal","family":"Jain","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA"},{"name":"Parkland Health and Hospital System, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy Yan-Shun","family":"Chow","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Kitchell","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Lazarte","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ank","family":"Nijhawan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"key":"bibr1-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2017.05.018"},{"key":"bibr2-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir990"},{"key":"bibr3-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1086\/322622"},{"key":"bibr4-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1254-6"},{"key":"bibr5-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2005.19.626"},{"key":"bibr6-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy506"},{"key":"bibr7-23259582211043863","doi-asserted-by":"publisher","DOI":"10.1086\/424877"},{"issue":"9","key":"bibr8-23259582211043863","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1093\/cid\/ciu094","volume":"58","author":"Masur H","year":"2014","journal-title":"Clin Infect Dis"},{"key":"bibr9-23259582211043863","unstructured":"Understanding the HIV Care Continuum. 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