{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:15:25Z","timestamp":1789600525721,"version":"build-2803163510"},"reference-count":45,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Navamindradhiraj University Research Fund","award":["13\/2564"],"award-info":[{"award-number":["13\/2564"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anemia is among the frequently observed conditions among people living with HIV (PLWH). Zidovudine (AZT) is the most common ART that causes anemia. This study aimed to identify the incidence and risk factors of AZT-induced anemia in PLWH receiving AZT-containing regimens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was conducted on nonpregnant PLWH aged &gt;18 years who received AZT-containing regimens for &gt;6 months and had normal baseline hemoglobin levels. Data on medical history, clinical characteristics, and laboratory examination were collected. Cox proportional hazard regression analysis was performed to determine the risk factors of AZT-induced anemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 401 individuals were included in the study. In total, 71 individuals presented with AZT-induced anemia. The incidence rate of anemia was 1.98 per 100 person-years of observations. Female sex, low-normal baseline hemoglobin level, low recent and low baseline CD4 cell count were independently associated with an increased risk of anemia. However, a higher body mass index was independently associated with a decreased risk of anemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Routine screening, early detection, and treatment of anemia should be considered in PLWH receiving AZT-containing regimens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582251321577","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T01:06:32Z","timestamp":1739927192000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Incidence and Risk Factors of Zidovudine-Induced Anemia in Patients With HIV Infection Receiving Zidovudine-Containing Antiretroviral Therapy"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5010-6928","authenticated-orcid":false,"given":"Lakkana","family":"Boonyagars","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peerawit","family":"Thinpangnga","sequence":"additional","affiliation":[{"name":"Research Facilitation Division, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warangkana","family":"Munsakul","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,18]]},"reference":[{"key":"bibr1-23259582251321577","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2573-2"},{"key":"bibr2-23259582251321577","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199905280-00010"},{"key":"bibr3-23259582251321577","doi-asserted-by":"publisher","DOI":"10.2310\/6650.2001.33967"},{"key":"bibr4-23259582251321577","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2018.05.005"},{"issue":"4","key":"bibr5-23259582251321577","first-page":"359","volume":"132","author":"Sharma SK","year":"2010","journal-title":"Indian J Med Res"},{"key":"bibr6-23259582251321577","unstructured":"Panel on Treatment of HIV During Pregnancy and Prevention of Perinatal Transmission. Recommendations for the use of antiretroviral drugs during pregnancy and interventions to reduce perinatal HIV transmission in the United States. Department of Health and Human Services. January 31, 2023. (Accessed November 29, 2023) https:\/\/clinicalinfo.hiv.gov\/en\/guidelines\/perinatal"},{"key":"bibr7-23259582251321577","unstructured":"Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. 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