{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T02:44:25Z","timestamp":1778035465127,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Despite global declines in HIV incidence, new infections continue to rise in Latin America. Oral tenofovir-based HIV pre-exposure prophylaxis (PrEP) is effective and can reduce incidence where implemented. PrEP PERU is a prospective cohort study evaluating daily oral PrEP delivery at HIV\/AIDS service organizations (ASOs) in Peru.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We assessed 12-month PrEP retention and adherence among men who have sex with men (MSM) enrolled at 4 ASOs in Lima before the COVID-19 pandemic. The analysis included participants with \u226512 months of follow-up before the March 2020 lockdown. Follow-up visits occurred at weeks 4, 12, and quarterly thereafter. We used robust Poisson regression to evaluate associations between baseline characteristics and 2 outcomes: retention (attending \u22653 follow-up visits within 12 months) and optimal adherence (proportion of days covered \u226580%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 264 MSM who initiated PrEP, median age was 31 years (IQR: 27-37). Retention at 12 months was 71%, and 55% achieved optimal adherence. Retention was associated with age \u226530 and bisexual identity in adjusted models. Optimal adherence was associated with being employed at baseline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PrEP delivery through ASOs in Lima is feasible and supports sustained engagement among MSM. Targeted strategies are needed to improve outcomes among younger individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582251411793","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T18:04:22Z","timestamp":1767722662000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Implementation of Daily Oral PrEP at HIV\/AIDS Service Organizations in Lima, Peru: Early Findings From the PrEP PERU Demonstration Study"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1144-0138","authenticated-orcid":false,"given":"Pamela","family":"Ram\u00edrez","sequence":"first","affiliation":[{"name":"Universidad Nacional Mayor de San Marcos"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4769-7242","authenticated-orcid":false,"given":"Alexander J.","family":"Lankowski","sequence":"additional","affiliation":[{"name":"Fred Hutchinson Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5142-1954","authenticated-orcid":false,"given":"Jorge A.","family":"Gallardo-Cartagena","sequence":"additional","affiliation":[{"name":"Universidad Nacional Mayor de San Marcos"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2610-0136","authenticated-orcid":false,"given":"Pedro","family":"Gonzales","sequence":"additional","affiliation":[{"name":"Asociaci\u00f3n Civil Impacta Salud y Educaci\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3635-1107","authenticated-orcid":false,"given":"Javier","family":"Valencia","sequence":"additional","affiliation":[{"name":"Asociaci\u00f3n Civil Impacta Salud y Educaci\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4983-5725","authenticated-orcid":false,"given":"Javier R.","family":"Lama","sequence":"additional","affiliation":[{"name":"Asociaci\u00f3n Civil Impacta Salud y Educaci\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3713-4902","authenticated-orcid":false,"given":"Mey","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Asociaci\u00f3n Civil Impacta Salud y Educaci\u00f3n"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9802-1330","authenticated-orcid":false,"given":"Javier","family":"Salvatierra","sequence":"additional","affiliation":[{"name":"Epicentro"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6876-2824","authenticated-orcid":false,"given":"Hugo","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Epicentro"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4765-0548","authenticated-orcid":false,"given":"Robinson","family":"Cabello","sequence":"additional","affiliation":[{"name":"Asociaci\u00f3n Civil V\u00eda Libre, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2836-0174","authenticated-orcid":false,"given":"Kelika A.","family":"Konda","sequence":"additional","affiliation":[{"name":"University of Southern California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6020-8266","authenticated-orcid":false,"given":"Jorge L.","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Universidad Nacional Mayor de San Marcos"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the PrEP PERU Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Gobierno del Per\u00fa Ministerio de Salud Centro Nacional de Epidemiolog\u00eda Prevenci\u00f3n y Control de Enfermedades (CDC MINSA). 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