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This study determined the prevalence and factors associated with hyperglycemia among people living with HIV (PLWH) on DTG-based ART in Uganda.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional study among 219 systematically recruited PLWH on DTG-based ART for \u22651 year at a Health Centre IV in Central Uganda. Data were collected using a structured questionnaire, anthropometric measurements, and laboratory investigations. Logistic regression was performed to identify factors associated with hyperglycemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 219 participants, 45 had fasting glucose \u2265110\u2005mg\/dL, giving a hyperglycemia prevalence of 20.55% (95% confidence interval [CI]: 15.68%-26.45%). Overweight (aOR 8.11, 95% CI: 2.76-23.85,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) and abnormal waist-to-hip ratio (aOR 4.36, 95% CI: 1.23-15.37,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.022) were significantly associated with hyperglycemia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hyperglycemia is prevalent among PLWH on DTG-based ART and is potentially associated with overweight and abnormal waist-to-hip ratio.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582261426447","type":"journal-article","created":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T17:10:59Z","timestamp":1771866659000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence and Factors Associated With Hyperglycemia Among Patients on Dolutegravir-Based Antiretroviral Therapy: A Cross-Sectional Study From Central Uganda"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4235-1003","authenticated-orcid":false,"given":"Charles Nkubi","family":"Bagenda","sequence":"first","affiliation":[{"name":"Mbarara University of Science and Technology"},{"name":"Department of Medical Laboratory Science, Uganda Institute of Allied Health and Management Sciences, Kampala City, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Nantongo","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Science, Uganda Institute of Allied Health and Management Sciences, Kampala City, Uganda"},{"name":"Joint Clinical Research Centre"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3947-3864","authenticated-orcid":false,"given":"Michael Junior","family":"Mugisa","sequence":"additional","affiliation":[{"name":"Mbarara University of Science and Technology"},{"name":"Department of Medical Laboratory Technology, Mayanja Memorial Medical Training Institute, Mbarara City, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elastus","family":"Ssemwanga","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology, Mayanja Memorial Medical Training Institute, Mbarara City, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylivia Achieng","family":"Lumumba","sequence":"additional","affiliation":[{"name":"Mbarara University of Science and Technology"},{"name":"Technical University of Mombasa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Kikabi","sequence":"additional","affiliation":[{"name":"Kyankwanzi District Ntwetwe Health Centre IV"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritah","family":"Kiconco","sequence":"additional","affiliation":[{"name":"Mbarara University of Science and Technology"},{"name":"Soroti University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon Peter","family":"Rugera","sequence":"additional","affiliation":[{"name":"Mbarara University of Science and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,23]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Global H. 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