{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T16:12:46Z","timestamp":1786378366306,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To estimate the prevalence and patterns of cardiac abnormalities among adults with HIV attending antiretroviral therapy clinics in Ethiopia and to identify clinical predictors of dilated cardiomyopathy (DCM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multicenter cross-sectional study enrolled 312 adults with HIV from three tertiary hospitals in Addis Ababa. All participants underwent transthoracic echocardiography and standardized clinical assessment; multivariable logistic regression identified independent predictors of DCM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Echocardiographic abnormalities were detected in 42.1% of participants, including diastolic dysfunction (8.9%), left ventricular hypertrophy (8.9%), systolic dysfunction (6.1%), DCM (5.4%), coronary artery disease (3.9%), pericardial effusion (2.5%), and pulmonary hypertension (1.4%). DCM was independently associated with CD4\u2009&lt;\u2009200 cells\/mm\n                      <jats:sup>3<\/jats:sup>\n                      , antiretroviral therapy\u2013na\u00efve status, and BMI &lt;18.5\u2005kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Ethiopian adults with HIV had a high burden of largely asymptomatic cardiac disease. Integrating targeted echocardiographic screening into routine HIV care, prioritizing patients with advanced immunosuppression, lack of ART, or malnutrition, may improve early detection and management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582261444796","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T14:24:03Z","timestamp":1776867843000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["High Burden of Cardiac Abnormalities in Adults with HIV in Ethiopia: A Multicenter Cross-Sectional Study"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2733-7897","authenticated-orcid":false,"given":"Biniyam Fiseha","family":"Abera","sequence":"first","affiliation":[{"name":"Yekatit 12 Hospital Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0556-4071","authenticated-orcid":false,"given":"Mikiyas G.","family":"Teferi","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biruk T.","family":"Mengistie","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0061-6458","authenticated-orcid":false,"given":"Chernet T.","family":"Mengistie","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca Haile","family":"Tesfay","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1938-3422","authenticated-orcid":false,"given":"Caleb M.","family":"Hailemariam","sequence":"additional","affiliation":[{"name":"Yekatit 12 Hospital Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4127-4846","authenticated-orcid":false,"given":"Temesgen H.","family":"Gebremeskel","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gadisa","family":"Megersa","sequence":"additional","affiliation":[{"name":"University of Gondar College of Medicine and Health Sciences"},{"name":"Internal Medicine, San Joaquin General Hospital, French Camp, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"e_1_3_4_2_2","first-page":"297","article-title":"Prevalence of clinical cardiovascular disease risk factors among HIV-infected patients on antiretroviral treatment in a tertiary hospital in Ethiopia","volume":"14","author":"Woldeyes E","year":"2022","unstructured":"Woldeyes E, Fisseha H, Mulatu HA, et al. Prevalence of clinical cardiovascular disease risk factors among HIV-infected patients on antiretroviral treatment in a tertiary hospital in Ethiopia. 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