{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:08:36Z","timestamp":1777853316315,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Assoc Provid AIDS Care"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study assessed treatment outcomes, medication adherence, and associated factors among human immunodeficiency virus (HIV) patients receiving dolutegravir-based antiretroviral therapy (ART) at Tikur Anbessa Specialized Hospital, Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A hospital-based retrospective study was conducted from February to May 2024 using medical records of patients treated between 2018 and 2020. A total of 425 records were selected through random sampling. Sociodemographic, clinical, and treatment-related data were collected using a structured tool and analyzed with SPSS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among participants, 58.8% were female, and 76.0% were aged 31 to 60 years. Overall, medication adherence was 85.7%, and viral load suppression was achieved in 99.8% of patients. All patients were screened for tuberculosis, and 60% received isoniazid preventive therapy. Adherence was significantly associated with World Health Organization clinical stage, follow-up status, advanced HIV disease, and antiretroviral dose days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Dolutegravir-based ART showed excellent virologic outcomes and high adherence levels, highlighting key factors influencing treatment success.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582261446464","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:40:51Z","timestamp":1777041651000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Treatment Outcome, Medication Adherence, and Associated Factors After the Introduction of Dolutegravir-Based Antiretroviral Therapy (ART) Regimen Among HIV\/AIDS Patients in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9676-8943","authenticated-orcid":false,"given":"Zenebe","family":"Negash","sequence":"first","affiliation":[{"name":"Addis Ababa University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonatan","family":"Fekadu","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengistu Girma","family":"Tirore","sequence":"additional","affiliation":[{"name":"Wachemo University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zelalem Tilahun","family":"Tesfaye","sequence":"additional","affiliation":[{"name":"Addis Ababa University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malede Berihun","family":"Yismaw","sequence":"additional","affiliation":[{"name":"Bahir Dar University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"e_1_3_4_2_2","unstructured":"UNAIDS. Global HIV & AIDS statistics. Fact sheet: 2023. https:\/\/www.unaids.org\/en\/resources\/fact-sheet."},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0275560"},{"key":"e_1_3_4_4_2","unstructured":"UNAIDS. 90-90-90: An ambitious treatment target to help end the AIDS epidemic. 2019. https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/90-90-90_en.pdf."},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-2918(08)80048-3"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12981-020-00294-z"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2022.0502"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkad102"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000003878"},{"issue":"1","key":"e_1_3_4_10_2","first-page":"2965325","article-title":"Could a dolutegravir-based antiretroviral therapy lead to clinical obesity? 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