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In Canada and globally, these intersecting inequities are exacerbated by limited, biomedical, and colonial models of care that overlook women's needs, leaving them underserved in HIV and sexually transmitted and blood-borne infection (STBBI) prevention. Our study describes the development of the Women-Centred Prevention (W-PREV) Model, designed to integrate HIV\/STBBI prevention and SRH through an intersectional, women-led approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Guided by the implementation science Knowledge-to-Action Framework, we adapted the existing Women-Centred HIV Care (WCHC) Model to address HIV\/STBBI prevention and SRH needs for women. The development process included a rapid scoping review, environmental scan, and stakeholder interviews with women, clinicians, and service providers in two Canadian provinces, Ontario and Saskatchewan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Findings highlighted that structural barriers such as housing insecurity, stigma, and systemic racism often overshadow women's ability to prioritize HIV\/STBBI prevention and SRH. The resulting W-PREV Model addresses these realities by integrating HIV\/STBBI prevention within six interrelated domains: SRH care, gender-specific care, mental health care, substance use and harm reduction, social connection and peer support, and individual capacity building. The model's trauma- and violence-aware, person-centred, and culturally responsive foundation ensures prevention is accessible, relevant, and empowering across the life course. W-PREV is distinct in its focus on HIV\/STBBI prevention and early intervention, integrating SRH, peer support, and outreach within community and clinical settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The W-PREV Model provides a comprehensive, women-centred framework that bridges clinical and community settings to support personalized HIV\/STBBI prevention and SRH self-care. By grounding prevention in women's lived experiences and peer support, W-PREV promotes equitable, holistic, and sustainable care for women and gender diverse people in Canada.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582261447168","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T13:11:39Z","timestamp":1778245899000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of the W-PREV Model: Integrating HIV\/STBBI Prevention and Women's Sexual and Reproductive Healthcare Using an Intersectional Women-Centered Approach"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9990-5949","authenticated-orcid":false,"given":"Kyla","family":"Gibson","sequence":"first","affiliation":[{"name":"Women's College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Ly","sequence":"additional","affiliation":[{"name":"Women's College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7478-8596","authenticated-orcid":false,"given":"V Logan","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Women's College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Underhill","sequence":"additional","affiliation":[{"name":"Women's College Hospital"},{"name":"University of Guelph"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Smith","sequence":"additional","affiliation":[{"name":"Women's College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Bear","sequence":"additional","affiliation":[{"name":"Wellness Wheel Clinic, Regina, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cara","family":"Spence","sequence":"additional","affiliation":[{"name":"Wellness Wheel Clinic, Regina, Canada"},{"name":"University of Saskatchewan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wangari","family":"Tharao","sequence":"additional","affiliation":[{"name":"Women's Health in Women's Hands, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molly","family":"Bannerman","sequence":"additional","affiliation":[{"name":"Women and HIV\/AIDS Initiative, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asli","family":"Mahdi","sequence":"additional","affiliation":[{"name":"Women and HIV\/AIDS Initiative, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ananya","family":"Inaganti","sequence":"additional","affiliation":[{"name":"Women's College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rsha","family":"Soud","sequence":"additional","affiliation":[{"name":"Women's College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley","family":"Lacombe-Duncan","sequence":"additional","affiliation":[{"name":"Women's College Hospital"},{"name":"School of Social Work, University of Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7887-8997","authenticated-orcid":false,"given":"Mona","family":"Loutfy","sequence":"additional","affiliation":[{"name":"Women's College Hospital"},{"name":"Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada"},{"name":"Maple Leaf Medical Clinic, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,5,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0283729"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12978-023-01594-z"},{"key":"e_1_3_3_4_2","unstructured":"Violence against women. 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