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Data were synthesized from 26 studies involving 77,760 prisoners across sub-Saharan Africa. A random-effects model was used to calculate pooled prevalence estimates, assess regional variation, and evaluate odds ratios (OR) for potential transmission risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall pooled prevalence was 13.0% for HBV and 8.0% for HCV among prisoners. Significant regional disparities were observed, with West Africa presenting the highest HBV burden (16.3%) and East Africa showing the highest HCV burden (8.8%). Key independent predictors of infection included sharing sharp objects (OR, 1.98), tattooing (OR, 1.92), and intravenous drug use (OR, 1.38).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Incarcerated populations in sub-Saharan Africa experience a high burden of viral hepatitis driven by parenteral exposure and high-risk sexual interactions. Addressing these gaps requires targeted screening, comprehensive harm reduction, condom provision, and integrating prison health services into national elimination strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/23259582261494741","type":"journal-article","created":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T15:05:11Z","timestamp":1791731111000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Hepatitis B and C Virus Among Prisoners in Sub-Saharan Africa: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0840-8707","authenticated-orcid":false,"given":"Tsegaamlak Kumelachew","family":"Derse","sequence":"first","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8087-9845","authenticated-orcid":false,"given":"Desalegn Mitiku","family":"Kidie","sequence":"additional","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5438-8237","authenticated-orcid":false,"given":"Addisu Simachew","family":"Asgai","sequence":"additional","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5489-3559","authenticated-orcid":false,"given":"Tadios","family":"lidetu","sequence":"additional","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yideg","family":"Abinew","sequence":"additional","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asaye Worku","family":"Agegn","sequence":"additional","affiliation":[{"name":"Debre Berhan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misganaw","family":"Alelign","sequence":"additional","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moges Tadesse","family":"Abebe","sequence":"additional","affiliation":[{"name":"Debark University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,11]]},"reference":[{"key":"e_1_3_4_2_2","first-page":"70","article-title":"Hepatitis B Virus (HBV)","volume":"12","author":"Ayanyinka A","year":"2025","unstructured":"Ayanyinka A, Oyelayo I, Okediji A, et al. 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