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Pneumoniae meningoencephalitis in a full term 6-month-old which progressed to multiple cerebral and cerebellar infarcts with concomitant cerebellar tonsillar herniation and hypercarbic respiratory failure requiring intubation and mechanical ventilation despite early initiation of antibiotics. Given the patient's clinical status and poor neurological prognosis, the family eventually opted for palliative extubation.<\/jats:p>","DOI":"10.1177\/2329048x241227341","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T02:14:26Z","timestamp":1705544066000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Severe Case of\n                    <i>Streptococcus pneumoniae<\/i>\n                    Meningoencephalitis in an Infant Resulting in Fatal Strokes"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2460-6178","authenticated-orcid":false,"given":"Michelle","family":"Goodman","sequence":"first","affiliation":[{"name":"Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6022-9059","authenticated-orcid":false,"given":"Mekka R.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidy","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria J.","family":"Borja","sequence":"additional","affiliation":[{"name":"Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devorah","family":"Segal","sequence":"additional","affiliation":[{"name":"Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"bibr1-2329048X241227341","volume-title":"Principles and Practice of Pediatric Infectious Diseases E-Book","author":"Long SS","year":"2022","edition":"6"},{"key":"bibr2-2329048X241227341","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0001-8"},{"key":"bibr3-2329048X241227341","doi-asserted-by":"publisher","DOI":"10.1086\/344939"},{"key":"bibr4-2329048X241227341","unstructured":"Ma\u0144dziuk J, Kuchar EP. Streptococcal Meningitis. [Updated 2023 Apr 10]. In: StatPearls [Internet]. 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