{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T05:03:47Z","timestamp":1793163827436,"version":"4.5.0"},"reference-count":58,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trends in Hearing"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>The purpose of this study was to test the hypothesis that listeners with frequent exposure to loud music exhibit deficits in suprathreshold auditory performance consistent with cochlear synaptopathy. Young adults with normal audiograms were recruited who either did ( n\u2009=\u200931) or did not ( n\u2009=\u200930) have a history of frequent attendance at loud music venues where the typical sound levels could be expected to result in temporary threshold shifts. A test battery was administered that comprised three sets of procedures: (a) electrophysiological tests including distortion product otoacoustic emissions, auditory brainstem responses, envelope following responses, and the acoustic change complex evoked by an interaural phase inversion; (b) psychoacoustic tests including temporal modulation detection, spectral modulation detection, and sensitivity to interaural phase; and (c) speech tests including filtered phoneme recognition and speech-in-noise recognition. The results demonstrated that a history of loud music exposure can lead to a profile of peripheral auditory function that is consistent with an interpretation of cochlear synaptopathy in humans, namely, modestly abnormal auditory brainstem response Wave I\/Wave V ratios in the presence of normal distortion product otoacoustic emissions and normal audiometric thresholds. However, there were no other electrophysiological, psychophysical, or speech perception effects. The absence of any behavioral effects in suprathreshold sound processing indicated that, even if cochlear synaptopathy is a valid pathophysiological condition in humans, its perceptual sequelae are either too diffuse or too inconsequential to permit a simple differential diagnosis of hidden hearing loss.<\/jats:p>","DOI":"10.1177\/2331216517737417","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T05:05:05Z","timestamp":1509944705000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":109,"title":["Loud Music Exposure and Cochlear Synaptopathy in Young Adults: Isolated Auditory Brainstem Response Effects but No Perceptual Consequences"],"prefix":"10.1177","volume":"21","author":[{"given":"John H.","family":"Grose","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of North Carolina at Chapel Hill, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Buss","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of North Carolina at Chapel Hill, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Joseph W.","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of North Carolina at Chapel Hill, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,11,6]]},"reference":[{"key":"bibr1-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1121\/1.3523476"},{"key":"bibr2-2331216517737417","doi-asserted-by":"publisher","DOI":"10.3109\/03005367909078884"},{"key":"bibr3-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1121\/1.4966113"},{"key":"bibr4-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3915-14.2015"},{"issue":"26","key":"bibr5-2331216517737417","first-page":"1","volume":"8","author":"Bharadwaj H. 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J. (1948) Findings indicating rationally applied therapy\u2014Part X. Deafness, tinnitus, and vertigo, New York, NY: Nelson, pp. 279\u2013285."},{"key":"bibr22-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2845-09.2009"},{"key":"bibr23-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2015.02.009"},{"issue":"58","key":"bibr24-2331216517737417","first-page":"100","volume":"14","author":"Kumar U. A.","year":"2012","journal-title":"Noise Health"},{"key":"bibr25-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1121\/1.423054"},{"key":"bibr26-2331216517737417","unstructured":"Le Prell, C. G. & Lobarinas, E. (2016).\n                      Lack of correlation between recreational noise history and performance on the Words-In-Noise (WIN) Test among normal hearing young adults\n                      . Paper presented at the Association for Research in Otolaryngology 39th MidWinter Meeting, San Diego, CA."},{"key":"bibr27-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-015-0510-3"},{"key":"bibr28-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162726"},{"key":"bibr29-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-011-0277-0"},{"key":"bibr30-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4460-15.2016"},{"key":"bibr31-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1121\/1.389861"},{"key":"bibr32-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-198401000-00011"},{"key":"bibr33-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1177\/014107688808100613"},{"key":"bibr34-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-199312000-00008"},{"key":"bibr35-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1177\/2331216516686768"},{"key":"bibr36-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1121\/1.1598197"},{"key":"bibr37-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1044\/jshd.2701.62"},{"key":"bibr38-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-69257-4_57"},{"key":"bibr39-2331216517737417","unstructured":"Prendergast, G., Guest, H., Hall, D. A., Kluk, K., Leger, A., Hickox, A. E. \u2026 Plack, C. J. (2016).\n                      An investigation of hidden hearing loss in young adults with normal hearing\n                      . Paper presented at the Association for Research in Otolaryngology, 39th MidWinter Meeting, San Diego, CA."},{"key":"bibr40-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2016.10.028"},{"key":"bibr41-2331216517737417","first-page":"75","volume":"48","author":"Quaranta A.","year":"1998","journal-title":"Scandinavian Audiology Supplement"},{"key":"bibr42-2331216517737417","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3109\/03005368809076457","volume":"22","author":"Rendell R. 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(2016).\n                      An investigation of musicians and \u201chidden hearing loss\u201d\n                      . Paper presented at the Audiology Australia National Conference, Melbourne, Australia."},{"key":"bibr57-2331216517737417","doi-asserted-by":"publisher","DOI":"10.1121\/1.393530"},{"key":"bibr58-2331216517737417","doi-asserted-by":"publisher","DOI":"10.3109\/03005369609078427"}],"container-title":["Trends in Hearing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2331216517737417","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2331216517737417","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2331216517737417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:42:29Z","timestamp":1777596149000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2331216517737417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":58,"alternative-id":["10.1177\/2331216517737417"],"URL":"https:\/\/doi.org\/10.1177\/2331216517737417","relation":{},"ISSN":["2331-2165","2331-2165"],"issn-type":[{"value":"2331-2165","type":"print"},{"value":"2331-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"article-number":"2331216517737417"}}