{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:48:16Z","timestamp":1788306496390,"version":"build-2803163510"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trends in Hearing"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>The aim of this study was to investigate surgical, anesthetic, and device-related complications associated with cochlear implantation (CI) in children younger than 1 year of age. This was a multicenter, retrospective chart review of all children with severe-to-profound sensorineural hearing loss who underwent cochlear implantation with a Cochlear Nucleus Implant System before 1 year of age. Endpoints included perioperative course, major and minor surgical, anesthetic and device-related complications, and 30-day readmission rates. One hundred thirty-six infants (242 ears) met criteria. The mean age at implantation was 9.4\u2009months (standard deviation 1.8). Six-month follow-up was reported in all patients. There were no major anesthetic or device-related complications. Adverse events were reported in 34 of implanted ears (14%; 7 major, 27 minor). Sixteen adverse events occurred \u226430\u2009days of surgery, and 18 occurred &gt;30\u2009days of surgery. The 30-day readmission rate was 1.5%. The rate of adverse events did not correlate with preexisting medical comorbidities or duration under anesthesia. There was no significant difference detected in complication rate for patients younger than 9\u2009months of age versus those 9 to 11\u2009months of age. This study demonstrates the safety of CI surgery in infants and supports reducing the indication for cochlear implantation to younger than 1 year of age for children with bilateral, profound sensorineural hearing loss obtaining a Cochlear Nucleus Implant System.<\/jats:p>","DOI":"10.1177\/23312165211014695","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T11:41:15Z","timestamp":1621856475000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Cochlear Implantation in Infants: Evidence of Safety"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2445-7454","authenticated-orcid":false,"given":"Nicholas L.","family":"Deep","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head & Neck Surgery, New York University Grossman School of Medicine, New York City, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3474-5572","authenticated-orcid":false,"given":"Patricia L.","family":"Purcell","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head & Neck Surgery, Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen A.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head & Neck Surgery, Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blake C.","family":"Papsin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head & Neck Surgery, Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Thomas","family":"Roland Jr.","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head & Neck Surgery, New York University Grossman School of Medicine, New York City, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan B.","family":"Waltzman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head & Neck Surgery, New York University Grossman School of Medicine, New York City, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,5,24]]},"reference":[{"key":"bibr1-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2273-3"},{"key":"bibr2-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1177\/0003489416660113"},{"key":"bibr3-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2013.03.016"},{"key":"bibr4-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000268712.00756.dd"},{"key":"bibr5-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200409000-00015"},{"key":"bibr6-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2333"},{"key":"bibr7-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110000903"},{"key":"bibr8-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1080\/00016480802495453"},{"key":"bibr9-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812441572"},{"key":"bibr10-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1177\/1084713810370039"},{"key":"bibr11-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.02.011"},{"key":"bibr12-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318214ea88"},{"key":"bibr13-23312165211014695","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20204"},{"key":"bibr14-23312165211014695","doi-asserted-by":"crossref","unstructured":"Dettman, S. 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