{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:38:09Z","timestamp":1793317089372,"version":"4.5.0"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013348","name":"Innosuisse - Schweizerische Agentur f\u00fcr Innovationsf\u00f6rderung","doi-asserted-by":"publisher","award":["InnoSuisse Grant Nr. 29547.1 IP-LS"],"award-info":[{"award-number":["InnoSuisse Grant Nr. 29547.1 IP-LS"]}],"id":[{"id":"10.13039\/501100013348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trends in Hearing"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>The objective to preserve residual hearing during cochlear implantation has recently led to the use of intracochlear electrocochleography (ECochG) as an intraoperative monitoring tool. Currently, a decrease in the amplitude of the difference between responses to alternating-polarity stimuli (DIF response), predominantly reflecting the hair cell response, is used for providing feedback. Including other ECochG response components, such as phase changes and harmonic distortions, could improve the accuracy of surgical feedback. The objectives of the present study were (1) to compare simultaneously recorded stepwise intracochlear and extracochlear ECochG responses to 500\u2005Hz tone bursts, (2) to explore patterns in features extracted from the intracochlear ECochG recordings relating to hearing preservation or hearing loss, and (3) to design support vector machine (SVM) and random forest (RF) classifiers of acoustic hearing preservation that treat each subject as a sample and use all intracochlear ECochG recordings made during electrode array insertion for classification. Forty subjects undergoing cochlear implant (CI) surgery at the Oslo University Hospital, St. Thomas\u2019 Hearing Implant Centre, or the University Hospital of Zurich were prospectively enrolled. In this cohort, DIF response amplitude decreases did not relate to postoperative acoustic hearing preservation. Exploratory analysis of the feature set extracted from the ECochG responses and preoperative audiogram showed that the features were not discriminative between outcome classes. The SVM and RF classifiers that were trained on these features could not distinguish cases with hearing loss and hearing preservation. These findings suggest that hearing loss following CI surgery is not always reflected in intraoperative ECochG recordings.<\/jats:p>","DOI":"10.1177\/23312165231220997","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T00:43:56Z","timestamp":1702860236000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Classification of Acoustic Hearing Preservation After Cochlear Implantation Using Electrocochleography"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2584-0458","authenticated-orcid":false,"given":"Leanne","family":"Sijgers","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torquil","family":"Sorensen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Soulby","sequence":"additional","affiliation":[{"name":"Hearing Implant Centre, Guy's and St. Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Boyle","sequence":"additional","affiliation":[{"name":"European Research Center, Advanced Bionics GmbH, Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Dalbert","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"R\u00f6\u00f6sli","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg Eigner","family":"Jablonski","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Oslo University Hospital, Oslo, Norway"},{"name":"Institute of Clinical Medicine, University of Oslo, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkmar","family":"Hamacher","sequence":"additional","affiliation":[{"name":"European Research Center, Advanced Bionics GmbH, Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Greisiger","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Hearing Implant Centre, Guy's and St. Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Craniofacial and Regenerative Biology, King's College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Huber","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3937-1266","authenticated-orcid":false,"given":"Flurin","family":"Pfiffner","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,12,17]]},"reference":[{"key":"bibr1-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000244355.34577.85"},{"key":"bibr2-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2021.108353"},{"key":"bibr3-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000001319"},{"key":"bibr4-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2020.108094"},{"key":"bibr5-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000972"},{"key":"bibr6-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822f09f2"},{"key":"bibr7-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000935"},{"key":"bibr8-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1126\/science.177.4046.356"},{"key":"bibr9-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.36.10.580"},{"key":"bibr10-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000659"},{"key":"bibr11-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.02-01-00001.1982"},{"key":"bibr12-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2006.07.013"},{"key":"bibr13-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-460X(70)80036-0"},{"key":"bibr14-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001906"},{"key":"bibr15-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003403"},{"key":"bibr16-23312165231220997","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00291"},{"key":"bibr17-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002773"},{"key":"bibr18-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000001288"},{"key":"bibr19-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003620"},{"key":"bibr20-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1177\/2331216521990594"},{"key":"bibr21-23312165231220997","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2013.869059"},{"key":"bibr22-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000001010"},{"key":"bibr23-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1121\/10.0000948"},{"key":"bibr24-23312165231220997","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.915302"},{"key":"bibr25-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000871"},{"key":"bibr26-23312165231220997","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003177"}],"container-title":["Trends 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