{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T08:01:58Z","timestamp":1777881718259,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"P.R.I.M.E. \u2013 Postdoctoral Researchers International Mobility Experience","award":["605728"],"award-info":[{"award-number":["605728"]}]},{"name":"People Programme (Marie Curie Actions) of the European Union\u2019s Seventh Framework Programme","award":["FP7\/20072013"],"award-info":[{"award-number":["FP7\/20072013"]}]},{"name":"Taube Kinder lernen h\u00f6ren e. V."},{"name":"Research Commission of the Medical Faculty of the Medical Center at the University of Freiburg"},{"name":"Hong Kong Health and Medical Research Fund","award":["06172296"],"award-info":[{"award-number":["06172296"]}]},{"name":"Hong Kong Health and Medical Research Fund","award":["11103823"],"award-info":[{"award-number":["11103823"]}]},{"name":"German Federal Ministry of Education and Research"},{"DOI":"10.13039\/501100001655","name":"Deutscher Akademischer Austauschdienst","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001655","id-type":"DOI","asserted-by":"publisher"}]},{"name":"MED-EL Medical Electronics, Innsbruck, Austria","award":["PVFR2019\/2"],"award-info":[{"award-number":["PVFR2019\/2"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trends in Hearing"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>It is widely known that users of cochlear implants (CIs) often show deficits in binaural hearing. In particular, interaural time difference (ITD) discrimination tends to be substantially worse in CI users. However, only very few studies have investigated how CI stimulation affects the \u201cprecedence effect\u201d (PE), and how this might be affected by abnormal hearing experience during development. We performed behavioral experiments to measure temporal weighting functions (TWFs) to quantify the PE in three different cohorts of rats: normally hearing (NH) acoustically stimulated, neonatally deafened (ND) CI-stimulated, and adult deafened (AD) CI-stimulated animals. Lateralization responses were recorded to bursts of eight stimulus pulses in which the ITD of each pulse varied independently, and probit analysis revealed the perceptual weight of each pulse. The NH and ND-CI cohorts were tested at 50, 300, and 900 pps; the AD-CI animals were tested only at 300 pps. The NH animals show a pronounced \u201conset dominance\u201d at higher pulse rates, that is, the weighting of the first pulse was much larger than for subsequent pulses, exactly as one would expect given previous studies on human listeners. In contrast, the TWFs for the ND-CI and AD-CI animals were much flatter, with a reduction of onset dominance by \u223c75%, especially for higher pulse rates. Since neither of our CI cohorts had any experience of reverberation in their electric hearing, we interpret these results to indicate that the PE may require domain-specific experience to develop.<\/jats:p>","DOI":"10.1177\/23312165261441709","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T13:37:24Z","timestamp":1776951444000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["When the First Pulse Fades: 75% Reduction in Precedence Effect in Cochlear Implanted Rats"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0124-9716","authenticated-orcid":false,"given":"Alexa N","family":"Buck","sequence":"first","affiliation":[{"name":"City University of Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8814-203X","authenticated-orcid":false,"given":"Tim","family":"Fleiner","sequence":"additional","affiliation":[{"name":"University of Freiburg"},{"name":"Faculty of Biology, University of Freiburg, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4724-5550","authenticated-orcid":false,"given":"Nicole","family":"Rosskothen-Kuhl","sequence":"additional","affiliation":[{"name":"University of Freiburg"},{"name":"Faculty of Biology, University of Freiburg, Freiburg, Germany"},{"name":"Bernstein Center Freiburg and Faculty of Biology, University of Freiburg, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2604-0057","authenticated-orcid":false,"given":"Jan WH","family":"Schnupp","sequence":"additional","affiliation":[{"name":"City University of Hong Kong"},{"name":"Gerald Choa Neuroscience Institute, Chinese University of Hong Kong, Sha Tin, Hong Kong (SAR China)"},{"name":"Department of Otolaryngology, Chinese University of Hong Kong, Sha Tin, Hong Kong (SAR China)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1121\/10.0001259"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.08.023"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-013-0406-z"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00243.2015"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.3436540"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-82978-4"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-30569-0"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-017-0628-6"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.401955"},{"key":"e_1_3_3_11_1","doi-asserted-by":"crossref","unstructured":"Ivanov A. Z. King A. J. Willmore B. D. Walker K. M. Harper N. S. (2022). Cortical adaptation to sound reverberation. https:\/\/doi.org\/10.7554\/eLife.75090","DOI":"10.7554\/eLife.75090.sa2"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-013-0378-z"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.2916587"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.5051640"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-022-01228-z"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.5099164"},{"issue":"4","key":"e_1_3_3_17_1","article-title":"Maturation of the precedence effect: Honoring Bill Hartmann\u2019s wisdom","volume":"157","author":"Litovsky R. Y.","year":"2025","unstructured":"Litovsky R. Y., Abdi R., Kumar A., Shelly G. (2025). Maturation of the precedence effect: Honoring Bill Hartmann\u2019s wisdom. 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