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As limited data is available to understand the experience of adults experiencing homelessness and their health during this time, the purpose of this study was to explore how COVID-19 may have impacted their mental health, substance use, and ways of coping in this population. Using community-based participatory research, a community advisory board was established and remote individual interviews with 21 adults experiencing homelessness and 10 providers were conducted in Skid Row, Los Angeles. Using a qualitative, data analytic approach, the following major themes emerged: (1) Negative Impact of COVID-19 on Mental Health; (2) Negative Impact of COVID-19 on Limitation of Harm Reduction Services; and (3) Coping Strategies Utilized During the COVID-19 Pandemic. More research is needed to understand the impact of this pandemic on underserved communities.<\/jats:p>","DOI":"10.1177\/23333936221108712","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T08:13:18Z","timestamp":1658909598000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Perceptions of Homeless Adults and Their Providers on Coping With the Impact of COVID-19 Pandemic on Mental Health, Substance Use, and Harm Reduction Services"],"prefix":"10.1177","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-6620","authenticated-orcid":false,"given":"Adeline M.","family":"Nyamathi","sequence":"first","affiliation":[{"name":"University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Gelberg","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine at University of California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darlene","family":"Lee","sequence":"additional","affiliation":[{"name":"University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Arce","sequence":"additional","affiliation":[{"name":"University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandria","family":"Patten-Jones","sequence":"additional","affiliation":[{"name":"University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kartik","family":"Yadav","sequence":"additional","affiliation":[{"name":"University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maniyah","family":"Goodwine","sequence":"additional","affiliation":[{"name":"University of California, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Alikhani","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maritas","family":"Yao","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia H.","family":"Chang","sequence":"additional","affiliation":[{"name":"Los Angeles County Department of Public Health, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benissa E.","family":"Salem","sequence":"additional","affiliation":[{"name":"University of California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"bibr1-23333936221108712","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.03.057"},{"key":"bibr2-23333936221108712","doi-asserted-by":"publisher","DOI":"10.1177\/1524839912461273"},{"key":"bibr3-23333936221108712","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18063035"},{"key":"bibr4-23333936221108712","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.4546"},{"key":"bibr5-23333936221108712","unstructured":"Centers For Disease Control and Prevention. 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