{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T16:47:54Z","timestamp":1777654074858,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Gerontology and Geriatric Medicine"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Nursing homes (NH) residents with COVID-19 can either be tested because of presence of core symptoms (S-based) or because of transmission prevention (TP-based). The investigated study sample included all NH residents who underwent SARS-CoV-2 RT-PCR testing between March 16, 2020 and May 31, 2020 ( n = 380). Clinical symptoms, temperature, and oxygen saturation were extracted from medical records, 7\u00a0days before to 14\u00a0days after testing. COVID-19 was confirmed in 81 (21%) residents; 36 (44%) S-based and 45 (56%) TP-based: 45. Cycle threshold (CT) values did not differ between the groups. In the 7\u00a0days prior to the test falling (32%), somnolence (25%) and fatigue (21%) occurred in both groups. Two days before the test, we observed a stronger decrease in oxygen saturation and an increase in temperature for the S-based group compared to the T-based group that remained up to 10\u00a0days after testing. Residents within the S-based group were 2.5 times more likely to increased mortality within 30\u00a0days than residents in the TP-based group (HR, 2.56; 95% 1.3\u20135.2). Although, 73% of the T-based group did eventually develop core symptoms. Thus, attention to falling and daily measures of temperature and oxygen saturation can contribute to earlier detection.<\/jats:p>","DOI":"10.1177\/23337214211055338","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T07:31:14Z","timestamp":1636615874000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"7","author":[{"given":"Kelly C.","family":"Paap","sequence":"first","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"},{"name":"Amsta Healthcare Organisation, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9015-7647","authenticated-orcid":false,"given":"Anouk M.","family":"van Loon","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarian M.","family":"van Rijs","sequence":"additional","affiliation":[{"name":"Amsta Healthcare Organisation, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Helmich","sequence":"additional","affiliation":[{"name":"Amsta Healthcare Organisation, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca M.","family":"Buurman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Geriatric Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Smalbrugge","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cees M. P. M.","family":"Hertogh","sequence":"additional","affiliation":[{"name":"Department of Medicine for Older People, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,11,11]]},"reference":[{"issue":"22","key":"bibr1-23337214211055338","first-page":"2081","volume":"382","author":"Arons M.","year":"2020","journal-title":"Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility. 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