{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:17:36Z","timestamp":1785453456229,"version":"3.56.0"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Gerontology and Geriatric Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    Purpose: Medication-related osteonecrosis of the jaw (MRONJ) caused by bisphosphonates (BPs) and denosumab (Dmab) is still a major oral adverse event caused by cancer treatment and may be under-recognized by private dental services. With the aim of reducing the prevalence of MRONJ, this study, which is a pilot study for a planned future large-scale survey, compared knowledge about MRONJ between dental hygienists (DHs) in private dental clinics and those in cancer center hospitals. Methods: We conducted a questionnaire-based survey regarding MRONJ between 1 November 2023 and 31 January 2024 on DHs at a cancer base hospital and a private clinic in Saitama, Japan. We statistically analyzed the data collected using the \u03c7\n                    <jats:sup>2<\/jats:sup>\n                    test or Fisher\u2019s exact test with the level of significance set at 5%. Results: This study included 10 in-hospital and 53 private clinic DHs. The in-hospital DHs had appropriate knowledge of MRONJ. However, compared with the in-hospital DHs, although the private clinic DHs knew that BPs are used for osteoporosis, significantly fewer had knowledge of Dmab ( p\u2009&lt;\u2009.001) or knew that BPs and Dmab could also be used to treat cancer (both p\u2009&lt;\u2009.001). In addition, few private clinic DHs were aware of MRONJ cases refractory to antibiotic treatment alone ( p\u2009=\u2009.012). Conclusion: These findings suggest that private clinic DHs have less knowledge of MRONJ than those in cancer base hospitals.\n                  <\/jats:p>","DOI":"10.1177\/23337214241292794","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T03:47:29Z","timestamp":1730346449000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Dental Hygienists\u2019 Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3804-6122","authenticated-orcid":false,"given":"Yosuke","family":"Iijima","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miki","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Amano","sequence":"additional","affiliation":[{"name":"Division of Applied Pharmaceutical Education and Research, Hoshi University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saya","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Applied Pharmaceutical Education and Research, Hoshi University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miki","family":"Fujimaru","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Uematsu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Hino","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohiko","family":"Sano","sequence":"additional","affiliation":[{"name":"Division of Applied Pharmaceutical Education and Research, Hoshi University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norio","family":"Horie","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8001-2121","authenticated-orcid":false,"given":"Hiroshi","family":"Sakagami","sequence":"additional","affiliation":[{"name":"Meikai University Research Institute of Odontology (M-RIO), Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,31]]},"reference":[{"key":"bibr1-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdm442"},{"key":"bibr2-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1513724"},{"key":"bibr3-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0196419"},{"key":"bibr4-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2684924"},{"key":"bibr5-23337214241292794","doi-asserted-by":"publisher","DOI":"10.2217\/17455057.4.3.219"},{"key":"bibr6-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2006.00391.x"},{"key":"bibr7-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyz034"},{"key":"bibr8-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2021.12.007"},{"key":"bibr9-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2525"},{"key":"bibr10-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2009.00409.x"},{"key":"bibr11-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1111\/idh.12122"},{"key":"bibr12-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(03)00720-1"},{"key":"bibr13-23337214241292794","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21041447"},{"key":"bibr14-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-022-06940-8"},{"key":"bibr15-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511420430"},{"key":"bibr16-23337214241292794","doi-asserted-by":"publisher","DOI":"10.5125\/jkaoms.2019.45.1.3"},{"key":"bibr17-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-2275"},{"key":"bibr18-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2008.00331.x"},{"key":"bibr19-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2022.02.008"},{"key":"bibr20-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.04.031"},{"key":"bibr21-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114516000684"},{"key":"bibr22-23337214241292794","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"bibr23-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1007\/s00774-020-01174-2"},{"key":"bibr24-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2016.06.011"},{"key":"bibr25-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2964-2"},{"key":"bibr26-23337214241292794","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-019-1819-1"}],"container-title":["Gerontology and Geriatric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23337214241292794","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/23337214241292794","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/23337214241292794","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:56:50Z","timestamp":1777445810000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/23337214241292794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":26,"alternative-id":["10.1177\/23337214241292794"],"URL":"https:\/\/doi.org\/10.1177\/23337214241292794","relation":{},"ISSN":["2333-7214","2333-7214"],"issn-type":[{"value":"2333-7214","type":"print"},{"value":"2333-7214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"23337214241292794"}}