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Increasing number of infants born with microcephaly and other congenital deformities were identified through studies that have highlighted the importance of prevention of transmission of Zika virus in pregnant women. Long-term outcomes in infants born with this infection are now better understood than at the time of onset of this outbreak. Topics covered in this review include the history, modes of transmission, diagnosis of suspected cases, pathophysiology, complications, and prevention of Zika virus infection.<\/jats:p>","DOI":"10.1177\/2333794x20919595","type":"journal-article","created":{"date-parts":[[2020,5,27]],"date-time":"2020-05-27T03:24:23Z","timestamp":1590549863000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["A to Z of Zika Virus: A Comprehensive Review for Clinicians"],"prefix":"10.1177","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8393-2863","authenticated-orcid":false,"given":"Harbir Singh","family":"Arora","sequence":"first","affiliation":[{"name":"Children\u2019s Hospital of Michigan, Detroit, MI, USA"},{"name":"Wayne State University School of Medicine, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,5,27]]},"reference":[{"key":"bibr1-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix405"},{"key":"bibr2-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.056\/NEJMra1808246"},{"key":"bibr3-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(54)90006-1"},{"key":"bibr4-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2017.03.001"},{"key":"bibr5-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.3201\/eid1408.080287"},{"key":"bibr6-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0805715"},{"key":"bibr7-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002681"},{"key":"bibr8-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.3201\/eid2110.150847"},{"key":"bibr9-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6503e1"},{"key":"bibr10-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6503e2"},{"key":"bibr11-2333794X20919595","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00651-6"},{"key":"bibr12-2333794X20919595","unstructured":"World Health Organization. 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