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Nineteen patients were newly diagnosed with CPP compared to 4 patients diagnosed with CPP during the previous 2\u2009years. The number of new patients diagnosed with CPP was significantly higher than the mean during the previous 2\u2009years ( P\u2009&lt;\u2009.001). There were more overweight patients with CPP during and after the lockdown ( P\u2009&lt;\u2009.05). These patients had also increased uterus length ( P\u2009&lt;\u2009.05) and more advanced bone age ( P\u2009&lt;\u2009.05). The increase in the incidence of central precocious puberty during and after the lockdown due to COVID 19 can be considered a serious consequence of the increased fat mass and an early indicator of the worsening of childhood obesity.<\/jats:p>","DOI":"10.1177\/2333794x221134565","type":"journal-article","created":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T00:29:32Z","timestamp":1670891372000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Increased Incidence of Precocious Puberty in Girls During COVID-19 Pandemic: Early Indicator of the Upcoming Childhood Metabolic Syndrome Pandemic?"],"prefix":"10.1177","volume":"9","author":[{"given":"Alaa","family":"Itani","sequence":"first","affiliation":[{"name":"Lebanese American University, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Abou Hamdan","sequence":"additional","affiliation":[{"name":"Lebanese American University, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawraa","family":"Zgheib","sequence":"additional","affiliation":[{"name":"Lebanese American University, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeina","family":"Ghandour","sequence":"additional","affiliation":[{"name":"Lebanese American University, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christy","family":"Costanian","sequence":"additional","affiliation":[{"name":"Lebanese American University, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5062-2516","authenticated-orcid":false,"given":"Ahlam","family":"Azar","sequence":"additional","affiliation":[{"name":"Lebanese American University, Beirut, Lebanon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,12,12]]},"reference":[{"key":"bibr1-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2012.9.1.25"},{"key":"bibr2-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2009.12.003"},{"key":"bibr3-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20106"},{"key":"bibr4-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1080\/03014460151056338"},{"key":"bibr5-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.4274\/jcrpe.v1i4.3"},{"key":"bibr6-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1056\/nejm198204293061707"},{"key":"bibr7-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0134656"},{"key":"bibr8-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2010.03.019"},{"key":"bibr9-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.4.505"},{"key":"bibr10-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-1813F"},{"key":"bibr11-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22813"},{"key":"bibr12-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-020-00682-2"},{"key":"bibr13-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-020-00931-3"},{"key":"bibr14-2333794X221134565","doi-asserted-by":"crossref","DOI":"10.4135\/9781506307633","author":"Bornstein MH","year":"2018","journal-title":"The SAGE Encyclopedia of Lifespan Human Development"},{"key":"bibr15-2333794X221134565","doi-asserted-by":"publisher","DOI":"10.1159\/000467393"},{"key":"bibr16-2333794X221134565","unstructured":"Growth charts \u2013 clinical growth charts. 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