{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:32:08Z","timestamp":1792794728037,"version":"4.5.0"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Pediatric Health"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Mesenchymal hamartoma (MH) is a benign liver tumor accounting for 3% to 8% of all liver tumors in children, commonly manifesting before 3\u2009years of life. Distinguishing MH from hepatoblastoma and other liver tumors relies on imaging and alpha-fetoprotein (which is usually within normal range in MH), before histologic examination. We report a case of a hepatic MH associated with elevated alpha-fetoprotein, leading to a misdiagnosis of hepatoblastoma and the administration of chemotherapy. We draw the attention to the diagnostic difficulty and pitfalls related to alpha-fetoprotein elevation in the setting of a liver tumor, and we highlight the importance of imaging and histology in establishing the diagnosis.<\/jats:p>","DOI":"10.1177\/2333794x231193560","type":"journal-article","created":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T07:36:27Z","timestamp":1692344187000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Mesenchymal Hamartoma With Elevated Alpha-Fetoprotein: A Diagnostic Pitfall"],"prefix":"10.1177","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4841-0423","authenticated-orcid":false,"given":"Amine","family":"Naggar","sequence":"first","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0736-386X","authenticated-orcid":false,"given":"Hajar","family":"Andour","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"Bensaghir","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1908-4272","authenticated-orcid":false,"given":"Badr","family":"Kabila","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaimae","family":"Ben Driss","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soukaina","family":"El Aouni","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monim","family":"Ochan","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mounir","family":"Kisra","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najat","family":"Lamalmi","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siham","family":"El Haddad","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazik","family":"Allali","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Latifa","family":"Chat","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospitals Center, Mohammed V University, Rabat, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,8,18]]},"reference":[{"issue":"1","key":"bibr1-2333794X231193560","first-page":"2541","volume":"4","author":"Apanasiewicz A.","year":"2019","journal-title":"J Pediatr Surg"},{"key":"bibr2-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.07.052"},{"issue":"4","key":"bibr3-2333794X231193560","first-page":"293","volume":"3","author":"Hiyama E.","year":"2014","journal-title":"Transl Pediatr"},{"key":"bibr4-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1016\/S0242-6498(04)94017-5"},{"key":"bibr5-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2013.09.003"},{"key":"bibr6-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2006.21.1.63"},{"key":"bibr7-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(84)80197-9"},{"key":"bibr8-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-815784"},{"key":"bibr9-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1016\/j.epsc.2017.03.012"},{"key":"bibr10-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.2003.00250.x"},{"key":"bibr11-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2018-0803"},{"key":"bibr12-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000002607"},{"key":"bibr13-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.1590\/0100-3984.2015.0163"},{"key":"bibr14-2333794X231193560","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v6.i7.486"}],"container-title":["Global Pediatric Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2333794X231193560","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2333794X231193560","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2333794X231193560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:06:32Z","timestamp":1777446392000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2333794X231193560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":14,"alternative-id":["10.1177\/2333794X231193560"],"URL":"https:\/\/doi.org\/10.1177\/2333794x231193560","relation":{},"ISSN":["2333-794X","2333-794X"],"issn-type":[{"value":"2333-794X","type":"print"},{"value":"2333-794X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"article-number":"2333794X231193560"}}